SPAG4: A Protein Implicated in Cancer and Tissue Maintenance (G6676)
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SPAG4: A Protein Implicated in Cancer and Tissue Maintenance
SPAG4 (Cancer/Tis Antigen 127) is a protein that is expressed in a variety of tissues throughout the body, including the breast, lung, liver, and gastrointestinal tract. It is a member of the SPAG gene family, which encodes a family of proteins that are involved in cell signaling and cytoskeletal organization. While SPAG4 is not well-known as a drug target or biomarker, research into its functions and potential clinical applications is ongoing.
SPAG4 is a 21-kDa protein that is expressed in a variety of tissues throughout the body, including the breast, lung, liver, and gastrointestinal tract. It is a member of the SPAG gene family, which encodes a family of proteins that are involved in cell signaling and cytoskeletal organization. The SPAG gene family has been identified in a variety of organisms, including humans, and is thought to be involved in the development and maintenance of tissues and organs.
SPAG4 is expressed in a variety of tissues throughout the body, including the breast, lung, liver, and gastrointestinal tract. It is a member of the SPAG gene family, which encodes a family of proteins that are involved in cell signaling and cytoskeletal organization. The SPAG gene family has been identified in a variety of organisms, including humans, and is thought to be involved in the development and maintenance of tissues and organs.
One of the key functions of SPAG4 is its role in cell signaling. SPAG4 is involved in the regulation of cell proliferation and differentiation, and is thought to play a role in the development of cancer. For example, studies have shown that SPAG4 is highly expressed in a variety of cancer tissues, and that it is involved in the development of cancer cell stem cells. Additionally, SPAG4 has been shown to play a role in the regulation of cell migration and invasion, which are important processes in the development of cancer.
SPAG4 has also been shown to be involved in the regulation of cytoskeletal organization. SPAG4 is a member of the tubulin family, which is involved in the regulation of cell division and the organization of cytoskeletal elements. The cytoskeleton is the structure that gives cells shape and provides support, and is thought to be involved in the regulation of many cellular processes, including cell division, migration, and invasion. SPAG4 is thought to be involved in the regulation of cytoskeletal organization by the cytoskeleton.
SPAG4 is also involved in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs, and is thought to be involved in the development and maintenance of tissues and organs. SPAG4 is involved in the regulation of cell adhesion by the cytoskeleton, and is thought to play a role in the development of cancer.
In addition to its role in cell signaling and cytoskeletal organization, SPAG4 has also been shown to be involved in the regulation of cell survival. SPAG4 is a member of the p53 gene family, which encodes a protein that is involved in the regulation of DNA damage. repair and cell survival. The p53 gene family is known for its role in the regulation of cell survival, and is thought to be involved in the development and maintenance of tissues and organs. SPAG4 is thought to be involved in the regulation of cell survival by the p53 gene family.
SPAG4 is also involved in the regulation of cell signaling and cytoskeletal organization. SPAG4 is a member of the
Protein Name: Sperm Associated Antigen 4
Functions: Involved in spermatogenesis. Required for sperm head formation but not required to establish and maintain general polarity of the sperm head. Required for anchoring and organization of the manchette. Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex. May anchor SUN3 the nuclear envelope. Involved in maintenance of the nuclear envelope integrity. May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail
The "SPAG4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPAG4 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
SPAG5 | SPAG5-AS1 | SPAG6 | SPAG7 | SPAG8 | SPAG9 | SPAM1 | SPANXA1 | SPANXA2-OT1 | SPANXB1 | SPANXB2 | SPANXC | SPANXD | SPANXN1 | SPANXN2 | SPANXN3 | SPANXN4 | SPANXN5 | SPARC | SPARCL1 | SPART | SPART-AS1 | SPAST | SPATA1 | SPATA12 | SPATA13 | SPATA13-AS1 | SPATA16 | SPATA17 | SPATA18 | SPATA19 | SPATA2 | SPATA20 | SPATA20P1 | SPATA21 | SPATA22 | SPATA24 | SPATA25 | SPATA2L | SPATA3 | SPATA3-AS1 | SPATA31A1 | SPATA31A2 | SPATA31A3 | SPATA31A5 | SPATA31A6 | SPATA31A7 | SPATA31C1 | SPATA31C2 | SPATA31D1 | SPATA31D3 | SPATA31E1 | SPATA32 | SPATA33 | SPATA4 | SPATA41 | SPATA42 | SPATA45 | SPATA46 | SPATA48 | SPATA5 | SPATA5L1 | SPATA6 | SPATA6L | SPATA7 | SPATA8 | SPATA8-AS1 | SPATA9 | SPATC1 | SPATC1L | SPATS1 | SPATS2 | SPATS2L | SPC24 | SPC25 | SPCS1 | SPCS2 | SPCS2P4 | SPCS3 | SPDEF | SPDL1 | SPDYA | SPDYC | SPDYE1 | SPDYE18 | SPDYE2 | SPDYE21 | SPDYE2B | SPDYE3 | SPDYE4 | SPDYE5 | SPDYE6 | SPDYE7P | SPDYE8 | SPDYE9 | SPECC1 | SPECC1L | SPECC1L-ADORA2A | SPEF1 | SPEF2