SRD5A2: A Potential Drug Target for Various Diseases (G6716)

Target Name: SRD5A2

NCBI ID: G6716

SRD5A2

SRD5A2: A Potential Drug Target for Various Diseases

SRD5A2 (S5A2_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, spinal cord, and peripheral tissues. It is a key regulator of the cell cycle, and is involved in the development and maintenance of normal cell structure and function. Unfortunately, SRD5A2 has also been identified as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The S5A2 gene is located on chromosome 6p21 and encodes a protein that is composed of 21 kDa. The protein has four known functions, including regulating the cell cycle, activating the DNA damage response, and modulating the levels of intracellular signaling pathways. It is also involved in the development and maintenance of normal brain structure and function, and is thought to play a key role in the regulation of neurotransmitter release and synaptic plasticity.

One of the key functions of SRD5A2 is its role in regulating the cell cycle. The cell cycle is the process by which cells grow, divide, and replicate their genetic material.SRD5A2 is involved in the regulation of the G1 phase of the cell cycle, which is the phase of cell growth and preparation for cell division. During the G1 phase, SRD5A2 helps to ensure that the cell has enough genetic material to divide, and also helps to prevent the cell from entering a state of dormancy.

In addition to its role in regulating the cell cycle, SRD5A2 is also involved in the regulation of the DNA damage response. The DNA damage response is the process by which the cell responds to damage to its DNA. SRD5A2 is thought to play a key role in the regulation of the DNA damage response, and is involved in the formation of a protein complex that helps to ensure that the DNA damage response is properly regulated.

SRD5A2 is also involved in the regulation of intracellular signaling pathways. It is thought to play a key role in the regulation of the levels of several intracellular signaling pathways, including the PI3K/Akt signaling pathway, the NF-kappa-B signaling pathway, and the TGF-β signaling pathway. These signaling pathways are involved in a wide range of cellular processes, including cell survival, growth, and differentiation.

In addition to its role in regulating the cell cycle and intracellular signaling pathways, SRD5A2 is also involved in the development and maintenance of normal brain structure and function. It is thought to play a key role in the regulation of neurotransmitter release and synaptic plasticity, and is involved in the development of normal brain structure and function.

The potential drug target status of SRD5A2 is due to its involvement in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Cancer cells have been shown to have increased levels of SRD5A2, and may use this protein to promote their growth and survival. Similarly, neurodegenerative diseases, such as Alzheimer's disease, have been linked to increased levels of SRD5A2 in the brain.

In conclusion, SRD5A2 is a protein that is involved in the regulation of the cell cycle, the DNA damage response, and intracellular signaling pathways. It is also involved in the development and maintenance of normal brain structure and function. The potential drug target status of SRD5A2 makes it an attractive target for the development of new treatments for various diseases. Further research is needed to fully understand the role of SRD5A2 in disease and to develop effective treatments.

Protein Name: Steroid 5 Alpha-reductase 2

Functions: Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology

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•   general information;
•   protein structure and compound binding;
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•   expression level;
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•   related combination drugs;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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