Target Name: SSB
NCBI ID: G6741
Review Report on SSB Target / Biomarker Content of Review Report on SSB Target / Biomarker
SSB
Other Name(s): SS-B/La protein | La autoantigen | La/SSB | la autoantigen | LARP3 | Sjogren syndrome antigen B (autoantigen La) | Lupus La protein | SSB variant 2 | autoantigen La | Autoantigen La | lupus La antigen | Small RNA binding exonuclease protection factor La, transcript variant 1 | SSB variant 1 | sjoegren syndrome type B antigen | La ribonucleoprotein domain family, member 3 | La | Lupus La antigen | La ribonucleoprotein | SS-B | small RNA binding exonuclease protection factor La | Sjoegren syndrome type B antigen | LA_HUMAN | Small RNA binding exonuclease protection factor La, transcript variant 2 | Sjogren syndrome antigen B

SSB Protein: A Potential Target for Cellular Signaling and Biomarker Development

SSB (SS-B/La protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the SS family of proteins, which are known for their role in intracellular signaling. While the exact function of SSB protein is not yet fully understood, it is possible that it plays a role in the regulation of cellular processes such as cell growth, differentiation, and survival.

One of the unique features of SSB protein is its ability to interact with a variety of different molecules. This allows it to be involved in a wide range of cellular processes, making it an attractive target for researchers looking for new drugs or biomarkers. For example, SSB has been shown to interact with a variety of signaling molecules, including TGF-β, PDGF, and NF-kappa-B. This suggests that it may be involved in the regulation of cellular processes that are influenced by these signaling pathways.

Another potential mechanism by which SSB may be involved in cellular signaling is its role in the regulation of protein synthesis. SSB is known to interact with the protein translation factor SSAP, which is involved in the delivery of new proteins to the endoplasmic reticulum. This suggests that SSB may be involved in the regulation of the translation of new proteins into the cell, potentially serving as a drug target for diseases characterized by the overproduction or underproduction of certain proteins.

In addition to its potential role in cellular signaling, SSB protein is also of interest as a potential biomarker. The over-expression of SSB protein has been shown to be associated with a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This suggests that SSB may be a useful diagnostic or therapeutic target for these diseases.

Furthermore, the structure and function of SSB protein are also of interest. The SSB protein is composed of a single polypeptide chain that is approximately 150 amino acids long. It has a characteristic Rossmann-fold, which is a type of hydrogen bonding that is involved in the formation of a stable beta-sheet structure. This structure is thought to give SSB protein its unique stability and stability, allowing it to function in a variety of cellular contexts.

In conclusion, SSB protein is an attractive target for research into the regulation of cellular processes and as a potential biomarker for a variety of diseases. Further studies are needed to fully understand its function and its potential as a drug or biomarker.

Protein Name: Small RNA Binding Exonuclease Protection Factor La

Functions: Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597)

The "SSB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SSB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1 | SSBP3P2 | SSBP4 | SSC4D | SSC5D | SSH1 | SSH2 | SSH3 | SSMEM1 | SSNA1 | SSPN | SSPOP | SSR1 | SSR1P2 | SSR2 | SSR3 | SSR4 | SSR4P1 | SSRP1 | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1 | SSU72 | SSU72L2 | SSU72P1 | SSU72P8 | SSUH2 | SSX1 | SSX2 | SSX2IP | SSX3 | SSX4 | SSX5 | SSX6P | SSX7 | SSX8P | SSX9P | SSXP10 | SSXP5 | ST13 | ST13P16 | ST13P18 | ST13P20 | ST13P4 | ST13P5 | ST14 | ST18 | ST20 | ST20-AS1 | ST20-MTHFS | ST3GAL1 | ST3GAL2 | ST3GAL3 | ST3GAL3-AS1 | ST3GAL4 | ST3GAL5 | ST3GAL5-AS1 | ST3GAL6 | ST3GAL6-AS1 | ST6GAL1 | ST6GAL2 | ST6GALNAC1 | ST6GALNAC2 | ST6GALNAC3 | ST6GALNAC4 | ST6GALNAC4P1 | ST6GALNAC5 | ST6GALNAC6 | ST7 | ST7-AS1 | ST7-OT3 | ST7-OT4 | ST7L | ST8SIA1 | ST8SIA2 | ST8SIA3 | ST8SIA4 | ST8SIA5 | ST8SIA6 | ST8SIA6-AS1 | STAB1 | STAB2 | STAC | STAC2 | STAC3 | STAG1 | STAG2 | STAG3 | STAG3L1 | STAG3L2 | STAG3L3 | STAG3L4 | STAG3L5P