Target Name: SRI
NCBI ID: G6717
Review Report on SRI Target / Biomarker Content of Review Report on SRI Target / Biomarker
SRI
Other Name(s): 22 kDa protein | Sorcin | Sorcin (isoform A) | calcium binding protein amplified in mutlidrug-resistant cells | Sorcin, transcript variant 1 | SORCN_HUMAN | SRI variant 1 | Calcium binding protein amplified in mutlidrug-resistant cells | SCN | V19 | sorcin | CP-22 | H_RG167B05.1 | CP22

SRI: A Protein Involved in Brain Development and Function

SRI (22 kDa protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is made up of 22 amino acid residues and has a calculated molecular weight of 23.9 kDa.

One of the unique features of SRI is its expression pattern. It is predominantly expressed in the brain, where it is found in the enolized neuronal nuclei. It is also expressed in the endoplasmic reticulum and in the cytoplasm of neuronal cells.

SRI has been shown to play a role in a number of cellular processes, including cell signaling, neurotransmitter release, and stress response. It is involved in the regulation of several signaling pathways, including the insulin/IGF-1 signaling pathway, the TGF- 尾 signaling pathway, and the Wnt signaling pathway.

SRI has also been shown to be involved in the regulation of cellular processes that are important for brain development and function, such as synaptic plasticity and learning. It is thought to play a role in the regulation of synaptic strength, as well as the modulation of neurotransmitter release and neuronal excitability.

SRI is also of interest as a potential drug target. Its unique expression pattern in the brain makes it an attractive target for small molecule inhibitors, which can be used to disrupt its functions and treat a variety of neurological and psychiatric disorders.

In addition to its potential as a drug target, SRI is also of interest as a biomarker. Its expression pattern is altered in a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. Therefore, it may be used as a diagnostic or therapeutic target in these disorders.

In conclusion, SRI is a protein that is expressed in various tissues throughout the body and is involved in a number of cellular processes. Its unique expression pattern in the brain makes it an attractive target for small molecule inhibitors, as well as a potential drug and biomarker. Further research is needed to fully understand its functions and potential uses in medicine.

Protein Name: Sorcin

Functions: Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels

The "SRI Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SRI comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1 | SRSF7 | SRSF8 | SRSF9 | SRXN1 | SRY | SS18 | SS18L1 | SS18L2 | SSB | SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1 | SSBP3P2 | SSBP4 | SSC4D | SSC5D | SSH1 | SSH2 | SSH3 | SSMEM1 | SSNA1 | SSPN | SSPOP | SSR1 | SSR1P2 | SSR2 | SSR3 | SSR4 | SSR4P1 | SSRP1 | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1 | SSU72 | SSU72L2 | SSU72P1 | SSU72P8 | SSUH2 | SSX1 | SSX2 | SSX2IP | SSX3 | SSX4 | SSX5 | SSX6P | SSX7 | SSX8P | SSX9P | SSXP10 | SSXP5 | ST13 | ST13P16 | ST13P18 | ST13P20