SRXN1: A Protein Involved in Neurotransmitter Signaling and Ion Channels

Target Name: SRXN1

NCBI ID: G140809

SRXN1

SRXN1: A Protein Involved in Neurotransmitter Signaling and Ion Channels

SRXN1 (SRXN1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, lungs, and liver. It is a member of the nuclear transport receptor subfamily, which is a family of transmembrane proteins that play a critical role in the transport of various molecules across the blood-brain barrier.

SRXN1 is involved in the transport of several different molecules, including neurotransmitters such as dopamine, serotonin, and endothelial factors. It is also involved in the regulation of ion channels, including the potassium channels that are responsible for maintaining the resting membrane potential of neurons.

SRXN1 is a potential drug target because of its involvement in the regulation of neurotransmitter signaling. Many neurotransmitters are involved in the treatment of various neurological and psychiatric disorders, including depression, anxiety, and schizophrenia. By targeting SRXN1, researchers may be able to develop new treatments for these disorders.

In addition to its potential as a drug target, SRXN1 is also a potential biomarker for certain neurological disorders. The regulation of neurotransmitter signaling by SRXN1 is disrupted in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. By studying the effects of drugs on SRXN1 function, researchers may be able to develop new treatments for these disorders.

SRXN1 is also involved in the regulation of ion channels, which are responsible for maintaining the resting membrane potential of neurons. The regulation of ion channels by SRXN1 is critical for maintaining the integrity of the neuronal membrane and for the proper functioning of neurons.

In addition to its functions in the regulation of neurotransmitter signaling and ion channels, SRXN1 is also involved in the regulation of cell survival. Studies have shown that SRXN1 plays a role in the regulation of cell survival by controlling the levels of intracellular reactive oxygen species ( ROS).

In conclusion, SRXN1 is a protein that is expressed in various tissues of the human body and is involved in the regulation of neurotransmitter signaling, ion channels, and cell survival. Its potential as a drug target and biomarker make it an attractive target for researchers to study and develop new treatments for various neurological disorders.

Protein Name: Sulfiredoxin 1

Functions: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 (PubMed:15448164, PubMed:15590625). Does not act on PRDX5 or PRDX6 (PubMed:15448164, PubMed:15590625). May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (PubMed:15448164, PubMed:15590625)

The "SRXN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SRXN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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