Target Name: TRAPPC10
NCBI ID: G7109
Review Report on TRAPPC10 Target / Biomarker Content of Review Report on TRAPPC10 Target / Biomarker
TRAPPC10
Other Name(s): trafficking protein particle complex subunit 10 | Trafficking protein particle complex subunit 10 | MGC126777 | EHOC-1 | TRAPP 130 kDa subunit | TPC10_HUMAN | trafficking protein particle complex subunit TMEM1 | FLJ54223 | TRS130 | FLJ55683 | FLJ54817 | TRS30 | TRAPP subunit TMEM1 | OTTHUMP00000109489 | TRAPPC10 variant 1 | Epilepsy holoprosencephaly candidate 1 protein | Protein GT334 | Transmembrane protein 1 | trafficking protein particle complex 10 | epilepsy holoprosencephaly candidate-1 protein | transport protein particle subunit TMEM1 | Trafficking protein particle complex subunit 10 (isoform a) | Trafficking protein particle complex subunit 130 | Trafficking protein particle complex subunit TMEM1 | TMEM1 | transmembrane protein 1 | trafficking protein particle complex subunit 130 | EHOC1 | Trafficking protein particle complex subunit 10, transcript variant 1 | GT334 | Transport protein particle subunit TMEM1 | NEDMISS | Epilepsy holoprosencephaly candidate-1 protein

TRAPPC10: A Protein Involved in Cell Signaling and Disease

Trafficking Protein Particle Complex Subunit 10 (TRAPPC10) is a protein that is expressed in various tissues and cells in the human body. It plays a critical role in the regulation of cell signaling pathways, and its dysfunction has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

TRAPPC10 is a member of the trafficking protein particle complex (TPC), which is a protein complex that is involved in the transport of various protein particles throughout the cell. The TPC is composed of a variety of different proteins, including TRAPPC10, which is known for its role in the assembly and disassembly of vesicles that transport proteins across the cell membrane.

One of the key functions of TRAPPC10 is its role in the regulation of the trafficking of the protein known as p16INK4a. p16INK4a is a well-known protein that is involved in the regulation of cell growth, apoptosis, and other processes that are important for cell signaling. It is often expressed in high levels in tissues and cells that are growing rapidly or have been damaged, and its dysfunction has been implicated in a number of diseases, including cancer.

TRAPPC10 is also involved in the regulation of the trafficking of other proteins, including the protein known as IDH1. IDH1 is a gene that is often mutated in cancer, and its dysfunction has been implicated in the development of many types of cancer. TRAPPC10 is thought to play a role in the regulation of IDH1-mediated signaling pathways, which are important for the growth and survival of cancer cells.

In addition to its role in regulating the trafficking of these proteins, TRAPPC10 is also involved in the regulation of the formation and disassembly of vesicles that transport these proteins across the cell membrane. This process is known as the endocytosis system, and it is important for the delivery of proteins to the cell's cytoplasm, where they can be used for various cellular processes.

TRAPPC10 is also involved in the regulation of the trafficking of proteins that are involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These proteins include the protein known as Tau, which is involved in the regulation of cell signaling pathways and is often lost in neurodegenerative diseases.

In conclusion, TRAPPC10 is a protein that is involved in the regulation of various cellular processes that are important for the health and survival of the human body. Its dysfunction has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a potential drug target or biomarker, TRAPPC10 is a promising target for researchers who are seeking to develop new treatments for these diseases.

Protein Name: Trafficking Protein Particle Complex Subunit 10

Functions: Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether

The "TRAPPC10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRAPPC10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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