TRAP1: A Drug Target / Disease Biomarker (G10131)

Target Name: TRAP1

NCBI ID: G10131

TRAP1

TRAP1: A Drug Target / Disease Biomarker

TRAP1 (Tissue Response to Antibiotic Treatment-1) is a protein that is expressed in various tissues and cells in the body. It is a potential drug target and has been identified as a biomarker for antibiotic resistance.

TRAP1 is a transmembrane protein that is involved in the regulation of bacterial flagellin expression and function. Flagellin is a protein that is expressed in many bacteria and is involved in their movement and invasion into host cells. TRAP1 is thought to play a role in the regulation of flagellin expression by binding to its extracellular domain and interacting with the cytoplasmic domain of the protein.

Studies have shown that TRAP1 is involved in the regulation of bacterial growth and has been implicated in the development of antibiotic resistance. In particular, TRAP1 has been shown to be involved in the regulation of the bacterial flagellin gene.

Research has also shown that TRAP1 is involved in the regulation of the production of other bacterial proteins, including the synthesis of the bacterial cell wall material peptidoglycan. This suggests that TRAP1 may be a potential drug target for bacteria that are resistant to currently available antibiotics.

In addition to its potential drug target properties, TRAP1 has also been shown to have potential as a biomarker for antibiotic resistance. The ability of TRAP1 to bind to different antibiotics and to regulate the expression of flagellin has led to the idea that it may be a useful indicator of the effectiveness of antibiotics and the risk of antibiotic resistance.

TRAP1 is also a potential drug target for cancer cells. Studies have shown that TRAP1 is involved in the regulation of cell division and has been implicated in the development of cancer. In particular, TRAP1 has been shown to be involved in the regulation of the production of mitochondrial enzymes, which are involved in cell division.

In conclusion, TRAP1 is a protein that is expressed in various tissues and cells in the body and has been shown to be involved in the regulation of bacterial flagellin expression and function, as well as the production of other bacterial proteins and the regulation of cell division. Its potential drug target and biomarker properties make it an attractive target for further research and may lead to the development of new treatments for bacterial and cancer-related diseases.

Protein Name: TNF Receptor Associated Protein 1

Functions: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA

The "TRAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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