PPP1R2P4: A Potential Drug Target and Biomarker for Protein Phosphatase 1-Regulated Inhibitor Subunit 2 Pseudogene 4

Target Name: PPP1R2P4

NCBI ID: G728970

PPP1R2P4

Other Name(s): Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 4 | protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 4

PPP1R2P4: A Potential Drug Target and Biomarker for Protein Phosphatase 1-Regulated Inhibitor Subunit 2 Pseudogene 4

Protein phosphatases (PPPs) are a family of enzymes that play a crucial role in cellular signaling pathways. These enzymes remove phosphate groups from protein targets, thereby regulating their activity and localizing them to specific cellular locations. PPP1R2P4, also known as PPP1R2P4 pseudogene 4, is a gene that encodes a protein that belongs to the PPP1R2P4 family. Despite its importance in cellular signaling pathways, PPP1R2P4 has not been well studied, and its potential drug targets or biomarkers are not well understood.

In this article, we will explore the potential drug target of PPP1R2P4 and its potential as a biomarker for various diseases. We will discuss the current understanding of the protein's structure and function, as well as its potential clinical applications.

Structure and Function

PPP1R2P4 is a 194-amino acid protein that belongs to the PPP1R2P4 family. This family is characterized by the presence of a catalytic core and a regulatory subunit that contains a hypervariable region (HVR) responsible for interacting with protein targets. PPP1R2P4 has a unique molecular structure, with a distinct N-terminus and a C-terminus that is involved in the interaction with protein targets.

The N-terminus of PPP1R2P4 contains a putative nucleotide-binding oligomerization domain (NBO domain), which is known to play a role in the regulation of protein stability and interactions. The C-terminus of PPP1R2P4 contains a regions that are involved in the regulation of protein function, including a zinc ion-binding domain and a protein-coding region.

Functional Studies

Several studies have demonstrated that PPP1R2P4 is involved in the regulation of cellular processes, including cell signaling pathways, DNA replication, and apoptosis.

For example, PPP1R2P4 has been shown to regulate the activity of the protein kinase Ago2, which is involved in the regulation of DNA replication and cell cycle progression. Additionally, PPP1R2P4 has been shown to play a role in the regulation of the stress response, including the response to ionizing radiation and hypoxia.

In addition to its role in cellular signaling pathways, PPP1R2P4 has also been shown to be involved in the regulation of protein stability and interactions. For example, studies have shown that PPP1R2P4 can interact with protein targets and regulate their stability.

Potential Drug Targets

The potential drug targets of PPP1R2P4 are not well understood, but several studies have identified potential targets that could be targeted by small molecules.

One potential drug target for PPP1R2P4 is the regulation of the activity of protein kinases, including the activity of Ago2. Small molecules that can inhibit the activity of Ago2 could be used to treat diseases that are characterized by the over- activity of this protein, such as cancer.

Another potential drug target for PPP1R2P4 is the regulation of the stress response. Small molecules that can inhibit the activity of PPP1R2P4 in the stress response could be used to treat diseases that are characterized by the failure of the stress response, such as neurodegenerative diseases.

Biomarkers

PPP1R2P4 has the potential to serve as a biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

For example, PPP1R2P4 has been shown to be involved in the regulation of the stress response, which is a key factor in the development

Protein Name: Protein Phosphatase 1 Regulatory Inhibitor Subunit 2 Pseudogene 4

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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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