Target Name: TINF2
NCBI ID: G26277
Review Report on TINF2 Target / Biomarker Content of Review Report on TINF2 Target / Biomarker
TINF2
Other Name(s): TRF1-interacting nuclear protein 2 | TERF1 interacting nuclear factor 2, transcript variant 1 | TIN2S | TINF2 variant 1 | TINF2 variant 2 | TERF1-interacting nuclear factor 2 | TERF1 interacting nuclear factor 2 | TERF1 (TRF1)-interacting nuclear factor 2 | DKCA3 | TERF2 | (TRF1)-interacting nuclear factor 2 variant 1 | TERF1-interacting nuclear factor 2 (isoform 1) | TINF2_HUMAN | TIN2L | TERF1-interacting nuclear factor 2 (isoform 2) | TIN2 | TERF1 interacting nuclear factor 2, transcript variant 2

TINF2: A Potential Drug Target and Biomarker for TRF1-Interacting Nuclear Protein 2

Abstract:

TINF2 (TRF1-Interacting Nuclear Protein 2) is a protein that has been identified as a potential drug target and biomarker for TRF1-Interacting Nuclear Protein 2 (TIPN2) in various diseases, including neurodegenerative disorders, cancer, and autoimmune diseases. This article will summarize the current understanding of TINF2 and its potential implications as a drug target and biomarker.

Introduction:

TINF2 (TRF1-Interacting Nuclear Protein 2) is a 22 kDa protein that is expressed in various tissues and cells, including brain, heart, and peripheral tissues. It is a key component of the nuclear envelope and plays a critical role in the regulation of gene expression and protein localization. TINF2 has been implicated in various diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.

Potential Drug Target and Biomarker:

TINF2 has been identified as a potential drug target and biomarker for TRF1-Interacting Nuclear Protein 2 (TIPN2) in various diseases. TRF1-Interacting Nuclear Protein 2 (TIPN2) is a protein that has been implicated in various diseases, including neurodegenerative disorders, cancer, and autoimmune diseases. TINF2 has been shown to interact with TIPN2 and may play a role in the regulation of TIPN2 function.

Studies have shown that TINF2 can modulate the expression of various genes, including genes involved in neurodegenerative disorders, cancer, and autoimmune diseases. For example, studies have shown that TINF2 can inhibit the translation of mRNAs involved in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Additionally, TINF2 has been shown to promote the translation of mRNAs involved in cancer and autoimmune diseases, such as colon cancer and rheumatoid arthritis.

In addition to its potential drug target properties, TINF2 has also been identified as a potential biomarker for various diseases. Studies have shown that TINF2 levels can be affected by various factors, including neurodegenerative disorders, cancer, and autoimmune diseases. For example, studies have shown that TINF2 levels can be decreased in individuals with Alzheimer's disease and other neurodegenerative disorders, and can be increased in individuals with cancer and autoimmune diseases.

Conclusion:

In conclusion, TINF2 is a protein that has been identified as a potential drug target and biomarker for TRF1-Interacting Nuclear Protein 2 (TIPN2) in various diseases. Its interaction with TIPN2 and ability to modulate the expression of various genes makes it a promising target for future research and development. Further studies are needed to fully understand the role of TINF2 as a drug target and biomarker for TIPN2 and its potential implications in various diseases.

Protein Name: TERF1 Interacting Nuclear Factor 2

Functions: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix

The "TINF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TINF2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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TIPARP | TIPARP-AS1 | TIPIN | TIPRL | TIRAP | TIRAP-AS1 | TJAP1 | TJP1 | TJP2 | TJP3 | TK1 | TK2 | TKFC | TKT | TKTL1 | TKTL2 | TLCD1 | TLCD2 | TLCD3A | TLCD3B | TLCD4 | TLCD4-RWDD3 | TLCD5 | TLDC2 | TLE1 | TLE1-DT | TLE2 | TLE3 | TLE4 | TLE5 | TLE6 | TLK1 | TLK2 | TLL1 | TLL2 | TLN1 | TLN2 | TLNRD1 | TLR1 | TLR10 | TLR12P | TLR2 | TLR3 | TLR4 | TLR5 | TLR6 | TLR7 | TLR8 | TLR8-AS1 | TLR9 | TLX1 | TLX1NB | TLX2 | TLX3 | TM2D1 | TM2D2 | TM2D3 | TM4SF1 | TM4SF1-AS1 | TM4SF18 | TM4SF19 | TM4SF19-AS1 | TM4SF19-DYNLT2B | TM4SF20 | TM4SF4 | TM4SF5 | TM6SF1 | TM6SF2 | TM7SF2 | TM7SF3 | TM9SF1 | TM9SF2 | TM9SF3 | TM9SF4 | TMA16 | TMA7 | TMBIM1 | TMBIM4 | TMBIM6 | TMC1 | TMC2 | TMC3 | TMC4 | TMC5 | TMC6 | TMC7 | TMC8 | TMCC1 | TMCC1-DT | TMCC2 | TMCC3 | TMCO1 | TMCO1-AS1 | TMCO2 | TMCO3 | TMCO4 | TMCO5A | TMCO5B | TMCO6 | TMED1