TLNRD1: A novel protein target for drug development and cancer diagnosis

Target Name: TLNRD1

NCBI ID: G59274

TLNRD1

TLNRD1: A novel protein target for drug development and cancer diagnosis

The protein TLNRD1 (Talin rod domain containing 1) has been identified as a potential drug target and biomarker for various diseases, including cancer. TLNRD1 is a unique protein that plays a crucial role in the regulation of photoreceptor function in the retina, which is responsible for transmitting visual information to the brain. The identification of TLNRD1 as a potential drug target has significant implications for the development of new treatments for a range of diseases.

The TLNRD1 protein

TLNRD1 is a 22kDa protein that is expressed in various tissues, including the brain, retina, and peripheral tissues. It is characterized by a unique rod domain that is responsible for its unique structure and function. The rod domain is a small region of the protein that is located at the N-terminus and is characterized by a characteristic 伪-helices loop.

The rod domain of TLNRD1 is unique because it contains a unique farnesylated cysteine residue, which is important for the regulation of protein stability and localization. Additionally, the rod domain of TLNRD1 contains a unique glycylation pattern, which is characterized by the presence of a N-glycosylated residue at its Asp-2 position.

TLNRD1 function

TLNRD1 is involved in the regulation of photoreceptor function in the retina. Photoreceptor cells in the retina are responsible for transmitting visual information to the brain, and TLNRD1 plays a critical role in the regulation of the structure and function of these cells. TLNRD1 is involved in the regulation of photoreceptor protein (PR) stability and localization, as well as the regulation of their dynamics.

TLNRD1 is also involved in the regulation of optic neuron function, which is responsible for transmitting visual information from the retina to the brain. TLNRD1 is involved in the regulation of the axon guidance molecule, optic nerve transport, and optic neuron survival.

Drug targeting TLNRD1

The identification of TLNRD1 as a potential drug target has significant implications for the development of new treatments for a range of diseases. One of the main advantages of targeting TLNRD1 is its specificity, as it is not involved in the regulation of other proteins that are important for protein function.

TLNRD1 is a good candidate for a drug that targets the production or degradation of TLNRD1. This is because TLNRD1 is a protein that is expressed in various tissues and is involved in the regulation of a wide range of cellular processes. Additionally, TLNRD1 is a protein that is highly conserved across different species, which makes it an attractive target for drug development.

TLNRD1 has been shown to play a role in the development and progression of a range of diseases, including cancer. For example, studies have shown that TLNRD1 is involved in the regulation of cancer cell growth and survival. Additionally, TLNRD1 has been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed in tumors.

Conclusion

TLNRD1 is a unique protein that plays a critical role in the regulation of photoreceptor function in the retina. Its unique rod domain and unique farnesylated cysteine residue, as well as its involvement in the regulation of photoreceptor protein stability and localization, make it an attractive target for drug development. The identification of TLNRD1 as a potential drug target has significant implications for the development of new treatments for a range of diseases. Further research is needed to understand the full function of TLNRD1 and to develop effective drugs that target it.

Protein Name: Talin Rod Domain Containing 1

Functions: Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells

The "TLNRD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TLNRD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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