UNC79: A Potential Drug Target and Biomarker for Neurological Disorders

Target Name: UNC79

NCBI ID: G57578

UNC79

UNC79: A Potential Drug Target and Biomarker for Neurological Disorders

UNC79 is a gene that encodes the protein known as the NALCN channel complex subunit. This protein plays a crucial role in the regulation of neurotransmitter release from neurons, which is essential for the proper functioning of the nervous system. The NALCN channel complex subunit is a protein that is expressed in high levels in the brain and is involved in the regulation of neurotransmitter release.

Recent studies have identified UNC79 as a potential drug target for the treatment of various neurological disorders, including depression, anxiety, and neurodegenerative diseases. This is because the NALCN channel complex subunit is involved in the regulation of neurotransmitter release, which is often disrupted in these disorders. By targeting this protein with drugs, researchers hope to restore normal neurotransmitter release and improve the symptoms of these disorders.

In addition to its potential as a drug target, UNC79 has also been identified as a potential biomarker for various neurological disorders. This is because the NALCN channel complex subunit is expressed at high levels in the brain and can be easily detected using techniques such as RNA sequencing or immunofluorescence. By analyzing the levels of UNC79 in brain tissue or fluids, researchers can gain insights into the levels of neurotransmitter release and track the progression of various neurological disorders.

UNC79 is also of interest to researchers because of its location on the genetic map. The NALCN channel complex subunit is located on chromosome 79, which is one of the most highly expressed genes in the brain. This suggests that UNC79 may be a good candidate for drug targeting, particularly if other genes are involved in its regulation.

Overall, UNC79 is a gene that has significant potential as a drug target and biomarker for the treatment of neurological disorders. Its involvement in the regulation of neurotransmitter release and its location on the genetic map make it an attractive target for researchers to investigate further. As more research is conducted on UNC79, it is likely that the potential benefits of targeting this protein will become clear.

Protein Name: Unc-79 Homolog, NALCN Channel Complex Subunit

Functions: Auxiliary subunit of the NALCN sodium channel complex, a voltage-gated ion channel responsible for the resting Na(+) permeability that controls neuronal excitability. Activated by neuropeptides substance P, neurotensin, and extracellular calcium that regulates neuronal excitability by controlling the sizes of NALCN-dependent sodium-leak current

The "UNC79 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UNC79 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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