UNC5D as A Potential Drug Target for Various Diseases (G137970)

Target Name: UNC5D

NCBI ID: G137970

UNC5D

UNC5D as A Potential Drug Target for Various Diseases

UNC5D (Pro34692) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the UNC family of proteins, which are known for their role in cell signaling and inflammation.

Recent studies have identified UNC5D as a potential drug target (or biomarker) for the treatment of various diseases, including cancer, diabetes, and neurological disorders. This is because UNC5D has been shown to play a role in the development and progression of these conditions, as well as in the regulation of immune responses and inflammation.

One of the key mechanisms by which UNC5D is involved in disease is its role in the regulation of inflammation. In addition to its role in the development of cancer, UNC5D has been shown to contribute to the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

In addition to its role in inflammation, UNC5D has also been shown to be involved in the regulation of cell signaling and the development of cancer. For example, studies have shown that UNC5D can inhibit the activity of the protein PD-L1, which is involved in immune surveillance and has been implicated in the development of cancer.

Furthermore, UNC5D has also been shown to be involved in the regulation of cell division and the development of cancer. For instance, studies have shown that UNC5D can promote the growth and division of cancer cells, a process that is critical for their development.

In addition to its role in cancer development, UNC5D has also been shown to contribute to the regulation of other important cellular processes, including cell adhesion, migration, and the regulation of the immune response.

Overall, UNC5D is a protein that has the potential to be a valuable drug target or biomarker for the treatment of a wide range of diseases. Its role in the regulation of inflammation, cell signaling, and cancer development makes it an attractive target for the development of new therapies. Further research is needed to fully understand the mechanisms of UNC5D's role in disease and to develop effective treatments based on this protein.

Protein Name: Unc-5 Netrin Receptor D

Functions: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity)

The "UNC5D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UNC5D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets