Target Name: CIAO2A
NCBI ID: G84191
Review Report on CIAO2A Target / Biomarker Content of Review Report on CIAO2A Target / Biomarker
CIAO2A
Other Name(s): MIP18 family protein FAM96A | cytosolic iron-sulfur assembly component 2A | Cytosolic iron-sulfur assembly component 2A, transcript variant 1 | Cytosolic iron-sulfur assembly component 2A (isoform a) | family with sequence similarity 96 member A | FAM96A | CIA2A_HUMAN | Cytosolic iron-sulfur assembly component 2A | CIA2A | CIAO2A variant 1 | FA96A_HUMAN

CIAO2A: A Protein Involved in Pain, Inflammation and Cell Signaling

CIAO2A, also known as FAM96A, is a protein that belongs to the MIP18 family. This family of proteins is known for their role in cell signaling and inflammation. CIAO2A is a 22-kDa protein that is expressed in a variety of tissues, including the brain, heart, and immune system.

One of the key functions of CIAO2A is its role in the regulation of pain. Pain is a critical signaling mechanism that helps the body to respond to injuries and damage. However, when pain becomes chronic and uncontrolled, it can be a source of significant suffering.

CIAO2A has been shown to play a key role in the regulation of pain signaling in the brain. Studies have shown that CIAO2A is highly expressed in the brain and that it is involved in the development of pain hypersensitivity. This is important because pain hypersensitivity can make it more difficult for people to manage their pain and can lead to chronic pain.

In addition to its role in pain regulation, CIAO2A has also been shown to be involved in inflammation. Chronic inflammation can contribute to a range of diseases, including heart disease and immune system disorders.

CIAO2A has been shown to be involved in the regulation of inflammation in the immune system. Studies have shown that CIAO2A is highly expressed in immune cells and that it is involved in the development of inflammation. This is important because chronic inflammation can contribute to the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

CIAO2A has also been shown to be involved in the regulation of cell signaling. Studies have shown that CIAO2A is involved in the regulation of a variety of cellular processes, including cell adhesion, migration, and the formation of blood vessels. This is important because these processes are critical for the development and maintenance of tissues and organs.

CIAO2A is also a potential drug target. Studies have shown that CIAO2A is involved in a variety of cellular processes that are important for the development and maintenance of tissues and organs. This makes it a potential target for a variety of therapies, including drugs that can modulate pain signaling, inflammation, and cell signaling.

In conclusion, CIAO2A is a protein that is involved in a variety of cellular processes that are important for the development and maintenance of tissues and organs. Studies have shown that CIAO2A is involved in the regulation of pain, inflammation, and cell signaling. This makes it a potential drug target and a promising target for the development of new therapies. Further research is needed to fully understand the role of CIAO2A in cellular processes and its potential as a drug target.

Protein Name: Cytosolic Iron-sulfur Assembly Component 2A

Functions: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227)

The "CIAO2A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CIAO2A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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CIAO2AP2 | CIAO2B | CIAO3 | CIAPIN1 | CIART | CIB1 | CIB2 | CIB3 | CIB4 | CIBAR1 | CIBAR1-DT | CIBAR1P1 | CIBAR1P2 | CIBAR2 | CIC | CICP10 | CICP11 | CICP17 | CICP25 | CICP5 | CICP7 | CIDEA | CIDEB | CIDEC | CIDECP1 | CIITA | CILK1 | CILP | CILP2 | CINP | CIP2A | CIPC | CIR1 | CIRBP | CIRBP-AS1 | CIROP | CISD1 | CISD1P1 | CISD2 | CISD3 | CISH | CIT | CITED1 | CITED2 | CITED4 | CIZ1 | CKAP2 | CKAP2L | CKAP4 | CKAP5 | CKB | CKLF | CKM | CKMT1A | CKMT1B | CKMT2 | CKMT2-AS1 | CKS1B | CKS1BP2 | CKS1BP5 | CKS1BP6 | CKS1BP7 | CKS2 | CLASP1 | CLASP2 | CLASRP | Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex | Clathrin | CLBA1 | CLC | CLCA1 | CLCA2 | CLCA3P | CLCA4 | CLCC1 | CLCF1 | CLCN1 | CLCN2 | CLCN3 | CLCN4 | CLCN5 | CLCN6 | CLCN7 | CLCNKA | CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22