Target Name: ALDH4A1
NCBI ID: G8659
Review Report on ALDH4A1 Target / Biomarker Content of Review Report on ALDH4A1 Target / Biomarker
ALDH4A1
Other Name(s): Aldehyde dehydrogenase family 4 member A1 | 1-pyrroline-5-carboxylate dehydrogenase | epididymis secretory sperm binding protein | ALDH4 | OTTHUMP00000002545 | OTTHUMP00000002544 | mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [Precursor] | AL4A1_HUMAN | Mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase | Aldehyde dehydrogenase 4 family member A1, transcript variant P5CDhL | ALDH4A1 variant P5CDhS | P5CDhL | P5CDh | aldehyde dehydrogenase family 4 member A1 | P5CDhS | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (isoform a) | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | Aldehyde dehydrogenase 4 family member A1, transcript variant P5CDhS | P5CD | aldehyde dehydrogenase 4 family member A1 | P5C dehydrogenase | L-glutamate gamma-semialdehyde dehydrogenase | ALDH4A1 variant P5CDhL

ALDH4A1: A Potential Drug and Alcohol Detoxification Protein

ALDH4A1 (Aldehyde dehydrogenase family 4 member A1) is a gene that encodes a protein involved in the detoxification of xenobiotics, such as drugs and environmental toxins, in the liver. The encoded protein is a member of the Aldehyde dehydrogenase family 4, which is responsible for the metabolism of a wide variety of compounds, including drugs and other xenobiotics.

The ALDH4A1 protein is expressed in many tissues and cells of the body, including the liver, and is involved in the detoxification of xenobiotics. It is a potential drug target or biomarker for a variety of diseases, including drug addiction, alcoholism, and liver disease.

Drug Addiction

Drug addiction is a serious disease that can have significant impacts on an individual's physical and mental health. The use of drugs can lead to physical dependence and addiction, as well as financial, legal, and social problems.

ALDH4A1 is involved in the detoxification of drugs, which is an important function for individuals who are struggling with drug addiction. The detoxification of drugs is a complex process that involves the liver and other tissues in the body. The ALDH4A1 protein is a key component of this process, as it helps to remove drugs from the body.

If an individual is struggling with drug addiction, a treatment plan may include a combination of medications, such asopium, codeine, and naltrexone, as well as support for recovery, such as counseling and behavioral therapy.

Alcoholism

Alcoholism is a chronic and often relapsing disease that can have significant impacts on an individual's physical and mental health. It is characterized by the excessive and compulsive consumption of alcohol, as well as other behavioral and mental health problems.

ALDH4A1 is involved in the detoxification of alcohol, which is an important function for individuals who are struggling with alcoholism. The detoxification of alcohol is a complex process that involves the liver and other tissues in the body. The ALDH4A1 protein is a key component of this process, as it helps to remove alcohol from the body.

If an individual is struggling with alcoholism, a treatment plan may include a combination of medications, such as benzodiazepines, and support for recovery, such as counseling and behavioral therapy.

Liver Disease

Liver disease is a serious condition that can have significant impacts on an individual's health and quality of life. It is characterized by the damage or dysfunction of the liver, which can be caused by a variety of factors, including alcohol, drugs, and other toxins.

ALDH4A1 is involved in the detoxification of a wide variety of toxins, including alcohol and drugs, which are potential causes of liver disease. The detoxification of these toxins is a complex process that involves the liver and other tissues in the body. The ALDH4A1 protein is a key component of this process, as it helps to remove these toxins from the body.

If an individual is concerned about liver disease, it is important to seek medical attention and to follow a treatment plan that is designed to prevent or manage liver damage. This may include a combination of medications, such as statins, and lifestyle changes, such as quitting smoking and following a healthy diet.

Conclusion

In conclusion, ALDH4A1 is a gene that encodes a protein involved in the detoxification of xenobiotics, including drugs and environmental toxins, in the liver. The encoded protein is a member of the Aldehyde dehydrogenase family 4, which is responsible for the metabolism of a wide variety of compounds, including drugs and other xenobiotics.

ALDH4A1 is involved in the detoxification of drugs and alcohol, which are potential causes of drug addiction and alcoholism, respectively. It is also involved in the detoxification of a wide variety of other toxins, including drugs and environmental toxins.

If an individual is struggling with

Protein Name: Aldehyde Dehydrogenase 4 Family Member A1

Functions: Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes

The "ALDH4A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ALDH4A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ALDH5A1 | ALDH6A1 | ALDH7A1 | ALDH8A1 | ALDH9A1 | Aldo-Keto Reductase Family 1 | ALDOA | ALDOAP2 | ALDOB | ALDOC | ALG1 | ALG10 | ALG10B | ALG11 | ALG12 | ALG13 | ALG14 | ALG1L10P | ALG1L13P | ALG1L1P | ALG1L2 | ALG1L5P | ALG1L7P | ALG1L8P | ALG2 | ALG3 | ALG5 | ALG6 | ALG8 | ALG9 | ALK | ALKAL1 | ALKAL2 | Alkaline Phosphatase (ALP) | ALKBH1 | ALKBH2 | ALKBH3 | ALKBH4 | ALKBH5 | ALKBH6 | ALKBH7 | ALKBH8 | ALLC | ALMS1 | ALMS1-IT1 | ALMS1P1 | ALOX12 | ALOX12-AS1 | ALOX12B | ALOX12P2 | ALOX15 | ALOX15B | ALOX15P1 | ALOX15P2 | ALOX5 | ALOX5AP | ALOXE3 | ALPG | Alpha-2 Adrenergic receptors | alpha-6 beta-2 Nicotinic receptor | alpha-Adrenoceptor | alpha-Amylase | alpha-beta T Cell Receptor Complex (TCR) | Alpha-crystallin | alpha-Mannosidase | alpha-Secretase | alpha1-Adrenoceptor | ALPI | ALPK1 | ALPK2 | ALPK3 | ALPL | ALPP | ALS2 | ALS2CL | ALX1 | ALX3 | ALX4 | ALYREF | AMACR | AMBN | AMBP | AMBRA1 | AMD1 | AMD1P2 | AMDHD1 | AMDHD2 | AMELX | AMELY | AMER1 | AMER2 | AMER3 | AMFR | AMH | AMHR2 | AMIGO1 | AMIGO2 | AMIGO3 | Amine oxidase (copper containing) | Amino acid hydroxylase