ALKBH7: A Potential Drug Target for Spermatog (G84266)

Target Name: ALKBH7

NCBI ID: G84266

ALKBH7

ALKBH7: A Potential Drug Target for Spermatog

ALKBH7 (also known as Spermatogenesis Associated 11) is a protein that is expressed in a variety of tissues, including testes, prostate, and compensatory response tissues. Its most striking feature is its important role in spermatogenesis. During spermatogenesis, ALKBH7 helps form tetrads, a critical step in spermatogenesis.

In recent years, researchers have discovered the role of ALKBH7 in spermatogenesis and are exploring its potential as a drug target or biomarker. For example, studies have shown that ALKBH7 can promote apoptosis during spermatogenesis, thereby having an important impact on the spermatogenesis process.

In addition, ALKBH7 can interact with other molecules during spermatogenesis. For example, it binds to tubulin, an important structural protein during spermatogenesis. These findings indicate that ALKBH7 plays an important role in spermatogenesis and may be a potential drug target or biomarker.

ALKBH7 may also play a role in other molecules during spermatogenesis. For example, studies have shown that ALKBH7 can bind to tubulin in the nucleolus, an important organelle during spermatogenesis. These findings indicate that ALKBH7 continues to play an important role in spermatogenesis and may be a potential drug target or biomarker.

In summary, ALKBH7 is a protein that plays an important role in spermatogenesis. With further research, ALKBH7 may be a potential drug target or biomarker that can help treat various diseases during spermatogenesis.

Protein Name: AlkB Homolog 7

Functions: May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism (By similarity)

The "ALKBH7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ALKBH7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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