Target Name: AMHR2
NCBI ID: G269
Review Report on AMHR2 Target / Biomarker Content of Review Report on AMHR2 Target / Biomarker
AMHR2
Other Name(s): Anti-Mullerian hormone receptor type 2, transcript variant 1 | Mullerian inhibiting substance type II receptor | Anti-Mullerian hormone receptor type II | AMHR2 variant 3 | anti-Muellerian hormone type-2 receptor | AMHR | AMHR2 variant 2 | AMH type II receptor | MIS type II receptor | anti-Mullerian hormone receptor, type II | Anti-Muellerian hormone type-2 receptor (isoform 3) | Muellerian inhibiting substance type II receptor | AMHR2 variant 1 | MISR2 | Anti-Mullerian hormone receptor type 2, transcript variant 2 | Anti-Muellerian hormone type-2 receptor | Anti-Muellerian hormone type-2 receptor (isoform 2) | Anti-Muellerian hormone type II receptor | Anti-Muellerian hormone type-2 receptor (isoform 1) | anti-Muellerian hormone type II receptor | Anti-Mullerian hormone receptor type 2, transcript variant 3 | MRII | MISRII | AMHR2_HUMAN | anti-Mullerian hormone receptor type 2

AMHR2: Key Regulator of Reproductive and Cellular Processes

AMHR2, or Anti-Mullerian Hormone Receptor Type 2, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the development and maintenance of normal reproductive processes in females.AMHR2 is a transmembrane protein that is composed of two distinct extracellular domains: an N-terminus domain and a C-terminus domain. The N-terminus domain is responsible for the protein's cytoplasmic localization, while the C-terminus domain is involved in the protein's interactions with other proteins.

AMHR2 is a key regulator of the cell cycle, and it is involved in the G1/S transition, which is the stage of cell growth where the cell prepares for cell division. During the G1/S transition, AMHR2 helps to regulate the growth of the cell and the amount of protein that is produced.

AMHR2 is also involved in the regulation of cell adhesion. It is a protein that is expressed in the plasma membrane of various cell types, including epithelial cells, and it is involved in the formation of tight junctions between these cells. tight junctions are specialized junctions that help to maintain the integrity of the plasma membrane and are critical for the proper functioning of many physiological processes.

AMHR2 is also involved in the regulation of cell signaling pathways. It is a receptor for several signaling pathways, including the TGF-β pathway and the Wnt pathway. The TGF-β pathway is a well-known signaling pathway that is involved in the regulation of cell growth, while the Wnt pathway is a signaling pathway that is involved in the development and maintenance of neural tissue.

AMHR2 is a potential drug target for several diseases. One of the main targets for AMHR2 is cancer. Cancer is a disease that is characterized by the uncontrolled growth and proliferation of cells. AMHR2 has been shown to play a role in the regulation of cell growth and the G1/S transition, which are critical processes that are involved in the development and progression of cancer.

AMHR2 has also been shown to be involved in the regulation of fetal development. Pregnancy is a critical process that is involved in the regulation of fetal development, and AMHR2 plays a role in this process. During pregnancy, AMHR2 helps to regulate the growth and development of the placenta, which is responsible for providing oxygen and nutrients to the developing fetus.

AMHR2 is also involved in the regulation of inflammation. Inflammation is a critical response of the immune system to the presence of foreign substances in the body. AMHR2 is involved in the regulation of inflammation by helping to regulate the production of pro-inflammatory cytokines.

AMHR2 is also involved in the regulation of pain. Pain is a critical sensation that is involved in the regulation of the body's response to harmful stimuli. AMHR2 is involved in the regulation of pain by helping to regulate the production of pain-sensitive neurotransmitters.

In conclusion, AMHR2 is a protein that is involved in several critical processes in the regulation of normal reproductive processes, cell growth and development, cell signaling pathways, and pain. As a result, AMHR2 is a potential drug target for several diseases, including cancer, fetal development, inflammation, and pain. Further research is needed to fully understand the role of AMHR2 in these processes and to develop effective treatments.

Protein Name: Anti-Mullerian Hormone Receptor Type 2

Functions: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone

The "AMHR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AMHR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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