VAMP4: A Potential Drug Target Or Biomarker for Various Diseases

Target Name: VAMP4

NCBI ID: G8674

VAMP4

VAMP4: A Potential Drug Target Or Biomarker for Various Diseases

VAMP4 (VAMPS4) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The VAMP4 gene is a member of the voltage-activated ion channel (VAC) gene family, which is known for its role in the regulation of ion channels and their functions in various biological processes.

The VAMP4 gene has four exons, which encode a protein that is composed of multiple domains, including an N-terminal transmembrane domain, a voltage-dependent ion channel (VDIC), and a C-terminal T-loop domain. The VAMP4 protein is a type of ion channel that is involved in the regulation of intracellular ion levels, which is critical for various cellular processes, including signaling, neurotransmission, and ion homeostasis.

Studies have shown that VAMP4 is involved in the regulation of a wide range of physiological processes, including the regulation of muscle contractions, the contraction of blood vessels, and the regulation of pain perception. Additionally, VAMP4 has been shown to be involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key reasons for the interest in VAMP4 as a drug target is its role in the regulation of ion channels and its potential to modulate the activity of other proteins that are involved in the regulation of ion channels. This is because many diseases are caused by the misregulation of ion channels, which can lead to the disruption of critical cellular processes.

For example, in cancer, the misregulation of ion channels is a common event that allows the cells to survive and grow out of control. Similarly, in neurodegenerative diseases, such as Alzheimer's disease, the misregulation of ion channels is a contributing factor to the degenerative changes that occur in the brain.

In addition to its potential as a drug target, VAMP4 has also been shown to be a potential biomarker for various diseases. The regulation of ion channels is a critical aspect of many biological processes, and changes in ion channel regulation can be indicative of the presence of certain diseases.

For example, the misregulation of ion channels has been implicated in the development of Alzheimer's disease, as studies have shown that the levels of certain ions, including VAMP4, are altered in the brains of people with Alzheimer's disease. Similarly, the regulation of ion channels has also been implicated in the development of other neurodegenerative diseases, such as Parkinson's disease and Huntington's disease.

In addition to its potential as a drug target and biomarker, VAMP4 is also of interest as a potential therapeutic target for a variety of other diseases. For example, the regulation of ion channels is involved in the regulation of many physiological processes, including muscle contractions, blood vessel dilation, and nerve signaling. This makes VAMP4 a potential target for drugs that are designed to modulate these processes.

In addition to its potential therapeutic applications, VAMP4 is also of interest as a potential research tool for the study of ion channel regulation and its role in various biological processes. The regulation of ion channels is a complex process, and the study of VAMP4 and its role in this process can provide valuable insights into the regulation of ion channels and their functions in the cell.

Overall, VAMP4 is a gene that has significant potential as a drug target or biomarker for a variety of diseases. Its involvement in the regulation of ion channels and its potential to modulate the activity of other proteins makes it an attractive target for drug development. Additionally, its potential as a research tool for the study of ion channel regulation and its role in various biological processes makes it a valuable addition to the toolkit of researchers studying these phenomena.

Protein Name: Vesicle Associated Membrane Protein 4

Functions: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule

The "VAMP4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VAMP4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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