Target Name: TNFRSF25
NCBI ID: G8718
Review Report on TNFRSF25 Target / Biomarker Content of Review Report on TNFRSF25 Target / Biomarker
TNFRSF25
Other Name(s): Death receptor beta | WSL-LR | Guanine nucleotide exchange factor 720 | TNF receptor superfamily member 25 | protein WSL-1 | apoptosis-mediating receptor DR3 | Apoptosis-inducing receptor AIR | TNF receptor superfamily member 25, transcript variant 4 | Lymphocyte-associated receptor of death | Tumor necrosis factor receptor superfamily member 25 (isoform 1) | TRAMP | TR3 | APO-3 | death receptor beta | tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) | Death domain receptor 3 | Apoptosis-mediating receptor DR3 | PH domain-containing family G member 5 | apoptosis-mediating receptor TRAMP | Tumor necrosis factor receptor superfamily member 25 | TNF receptor superfamily member 25, transcript variant 1 | Apoptosis inducing receptor AIR | Tumor necrosis factor receptor superfamily member 25 (isoform 4) | Apo-3 | death domain receptor 3 soluble form | TNFRSF12 | apoptosis inducing receptor | TNR25_HUMAN | DR3 | TNFRSF25 variant 1 | TNFRSF25 variant 4 | Tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein) | LARD | Death domain receptor 3 soluble form | Death receptor 3 | apoptosis-inducing receptor AIR | WSL-1 | Protein WSL-1 | Protein WSL | Apoptosis inducing receptor | PLEKHG5 | lymphocyte-associated receptor of death | Pleckstrin homology domain-containing family G member 5 | GEF720 | DDR3 | Apoptosis-mediating receptor TRAMP

TNFRSF25: Key Regulator of Inflammation and Tissue Repair

TNFRSF25 (TNF-receptor superfamily 25) is a protein that is expressed in various tissues throughout the body, including the nervous system, endothelial cells, and various immune cells. It is a key regulator of inflammation and immune responses, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of TNFRSF25 is its role as a Death Receptor, which is a protein that is involved in the process of cell death. When TNFRSF25 is activated, it can induce the production of pro-inflammatory cytokines, such as TNF-alpha, which can contribute to inflammation and tissue damage.

In addition to its role in cell death, TNFRSF25 is also involved in a number of other cellular processes that are important for tissue repair and regeneration. For example, it has been shown to play a key role in the regulation of stem cell proliferation and differentiation, and has been implicated in the development of various diseases, including cancer.

Given its involvement in a number of important cellular processes, TNFRSF25 has been considered as a potential drug target or biomarker for a variety of diseases. For example, there is evidence to suggest that inhibiting the activity of TNFRSF25 may have therapeutic benefits for a number of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease.

In addition to its potential therapeutic applications, TNFRSF25 is also an attractive biomarker for a variety of diseases. For example, it has been shown to be a reliable indicator of disease severity in various neurodegenerative diseases, and has been used as a diagnostic marker in a number of studies.

Overall, TNFRSF25 is a protein that has important roles in a number of cellular processes that are important for tissue repair and regeneration. Its potential as a drug target or biomarker for a variety of diseases makes it an important area of research for scientists and clinicians. Further studies are needed to fully understand its functions and potential therapeutic applications.

Protein Name: TNF Receptor Superfamily Member 25

Functions: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis

The "TNFRSF25 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TNFRSF25 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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