EGFL7: A Potential Drug Target for Neurological Diseases (G51162)

Target Name: EGFL7

NCBI ID: G51162

EGFL7

EGFL7: A Potential Drug Target for Neurological Diseases

The English GFL7 (EGF-like domain multiple 7, transcript variant 1) gene is a member of the EGF-like domain family, which is characterized by the presence of a highly conserved EGF-like domain in the extracellular domain of the protein. This family of genes is involved in various cellular processes, including cell signaling, cell adhesion, and tissue development. EGFL7 is a gene that has been identified as a potential drug target and biomarker.

Expression and Localization

EGFL7 is a highly expressed gene in human tissues, including the brain, heart, and liver. It is predominantly expressed in the brain, where it is found in the enol-modified neuron-specific enol-modified neuronal nuclei. The highest proportion. In addition, EGFL7 is also expressed in immune cells and embryonic tissues.

Function

The function of EGFL7 is being further studied. Research shows that EGFL7 plays an important role in the growth and development of neurons. It is closely related to the survival and apoptosis of neurons, and to the formation and regeneration of neuronal synapses. In addition, EGFL7 is also related to the function of immune cells and may play a role in immune response.

pharmacological significance

EGFL7 is a potential drug target. Due to its functions related to neuronal function and survival, EGFL7 is considered a therapeutic target for neurological diseases. Currently, there are several studies exploring EGFL7 as a drug to treat neurological diseases. For example, one study explored EGFL7's potential as a drug to treat Parkinson's disease. In addition, EGFL7 has been used as a target for drugs to treat other neurological diseases, including Alzheimer's disease and depression.

biological significance

EGFL7 is an important gene that is closely related to neuronal function and survival. Its function is being further studied and is considered a therapeutic target for neurological diseases. The pharmacological significance of studying EGFL7 is to discover new ideas for treating neurological diseases as a drug target, which provides a basis for the development of new treatment methods and drugs.

Protein Name: EGF Like Domain Multiple 7

Functions: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis

The "EGFL7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EGFL7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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