Regulation of Protein Translation, Degradation and Signaling Pathways By EFR3B

Target Name: EFR3B

NCBI ID: G22979

EFR3B

Regulation of Protein Translation, Degradation and Signaling Pathways By EFR3B

EFR3B, also known as OTTHUMP00000200945, is a protein that is expressed in the endoplasmic reticulum (ER) and is involved in the regulation of protein translation in the cell. The ER is a complex organelle that is responsible for the production and quality control of proteins that are exported from the cell. The function of EFR3B is to regulate the rate at which proteins are translated from mRNA to functional proteins.

One of the key functions of EFR3B is its role in the regulation of the translation of proteins involved in cell signaling pathways. Many proteins involved in cell signaling pathways, such as tyrosine kinases and G protein-coupled receptors, are synthesized and translated from mRNA in the ER. The level of these proteins at the cell surface is critical for their function, and the regulation of their translation is a critical step in their production. EFR3B is involved in this process by regulating the rate at which the necessary machinery for protein translation is available in the ER.

In addition to its role in regulating protein translation, EFR3B is also involved in the regulation of protein degradation. The ER is a dynamic organelle that is constantly producing and degrading proteins. The degradation of proteins is important for maintaining the homeostasis of the cell and for ensuring that the cell is able to respond quickly to changes in its environment. EFR3B is involved in this process by regulating the levels of proteins at the cell surface, as well as the rate at which they are degraded.

EFR3B is also involved in the regulation of cellular signaling pathways. Many signaling pathways involve the production and regulation of proteins that are involved in the cell's response to changes in its environment. EFR3B is involved in these processes by regulating the translation of proteins involved in these signaling pathways. For example, EFR3B has been shown to be involved in the regulation of the production of the protein known as PDGF-R2, which is involved in the regulation of cell growth and differentiation.

In conclusion, EFR3B is a protein that is involved in the regulation of protein translation, degradation, and cellular signaling pathways. Its role in these processes is critical for the proper functioning of the cell and for the regulation of cellular processes that are essential for the maintenance of life. Further research is needed to fully understand the functions of EFR3B and to develop new treatments for diseases that are related to its dysfunction.

Protein Name: EFR3 Homolog B

Functions: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3B probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825)

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