EFHC2: A Potential Drug Target for PDZR1 and Brain Development

Target Name: EFHC2

NCBI ID: G80258

EFHC2

EFHC2: A Potential Drug Target for PDZR1 and Brain Development

EFHC2 (MrX74) is a protein that is expressed in the brain and is known for its role in the regulation of neural stem cells (NSCs) proliferation and differentiation. Researchers have been interested in studying EFHC2 as a potential drug target or biomarker for various neurological diseases and psychiatric disorders due to its unique expression pattern in the brain.

EFHC2 is a heat shock protein (HSP) that is expressed in a variety of tissues, including the brain. HSPs are a family of transmembrane proteins that are involved in various cellular processes, including stress response, cytoplasmic organization, and protein-protein interactions. EFHC2 is a type of HSP that is characterized by its ability to form a stable complex with the protein tilpine-binding receptor (PDZR1) and its role in the regulation of PDZR1 function.

PDZR1 is a protein that is expressed in various tissues and is involved in the regulation of ion channels, including the brain. PDZR1 has been implicated in a variety of neurological and psychiatric disorders, including epilepsy, schizophrenia, and depression.

Research has shown that EFHC2 is a key regulator of PDZR1 function and that it plays a role in the regulation of PDZR1-mediated signaling pathways. Studies have also shown that EFHC2 is involved in the regulation of cellular processes that are important for brain development and plasticity , including cell proliferation, migration, and apoptosis.

In addition to its role in the regulation of PDZR1 function, EFHC2 has also been shown to be involved in the regulation of various other signaling pathways that are important for brain function. For example, studies have shown that EFHC2 is involved in the regulation of TGF -尾 signaling, a pathway that is involved in cell growth, differentiation, and stress response.

EFHC2 has also been shown to be involved in the regulation of the Wnt signaling pathway, a pathway that is involved in cell-cell signaling and the regulation of tissue structure. Wnt signaling is important for brain development and plasticity, and studies have shown that EFHC2 plays a role in the regulation of Wnt signaling in the brain.

In conclusion, EFHC2 is a protein that is expressed in the brain and is involved in the regulation of various cellular processes that are important for brain development and plasticity. The unique expression pattern of EFHC2 makes it an attractive target for research into the regulation of PDZR1 function and other signaling pathways that are important for brain function. Further research is needed to fully understand the role of EFHC2 in brain development and plasticity, and to determine its potential as a drug target or biomarker for various neurological and psychiatric disorders.

Protein Name: EF-hand Domain Containing 2

Functions: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating

The "EFHC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EFHC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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