SPACDR: A Calcium Ion Transporter in Cells (G402573)

Target Name: SPACDR

NCBI ID: G402573

SPACDR

Other Name(s): C7orf61 | sperm acrosome developmental regulator | uncharacterized protein C7orf61 | SACDR_HUMAN | Sperm acrosome developmental regulator

SPACDR: A Calcium Ion Transporter in Cells

SPACDR (C7orf61) is a protein that is expressed in almost all eukaryotic cells and plays an important role in a variety of physiological processes. Its full name is spinal cord precuticle protein-61, which is a calcium ion transporter. SPACDR is responsible for transporting and regulating the concentration of calcium ions within cells to maintain intracellular physiological functions.

The SPACDR gene is located in the human chromosome 7 (Xp) region and is a coding gene. It is known that SPACDR is composed of an open reading frame (ORF), which includes an N-terminal 伪-helix, a central 尾-page and a C-terminal domain. The amino acid sequence in the ORF can be divided into two main regions: the N-terminal 伪-helix and the C-terminal domain.

The function of SPACDR in cells is to maintain intracellular physiological functions by transporting and regulating the concentration of calcium ions. Calcium ions are important intracellular signaling molecules that can regulate many cellular functions, such as muscle contraction, neurotransmission, cell differentiation, etc. In neurons, calcium ions also regulate synaptic transmission and communication between neurons. SPACDR is responsible for transporting and regulating the concentration of calcium ions within cells, and maintains physiological functions within cells through this process.

The biological functions of SPACDR are also manifested in other aspects. SPACDR can interact with other proteins, such as SPOP (SPACDR interacting protein) and CREB2. These proteins can enhance the function of SPACDR and affect its localization and stability. SPACDR can also interact with certain medications, such as antidepressants and antihypertensives. These drugs can affect the activity and stability of SPACDR and may have an impact on the function of SPACDR.

SPACDR is a protein that plays an important role in cells. Variations in the SPACDR gene and dysfunction of the SPACDR protein may lead to many diseases. Therefore, studying the biological functions and pathological characteristics of SPACDR is of great significance for understanding and treating many diseases. Future research can focus on developing methods of drug intervention in the SPACDR protein to treat related diseases.

Protein Name: Sperm Acrosome Developmental Regulator

Functions: May play a role in acrosome formation and nucleus shaping during spermiogenesis

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