Target Name: SOX30
NCBI ID: G11063
Review Report on SOX30 Target / Biomarker Content of Review Report on SOX30 Target / Biomarker
SOX30
Other Name(s): SRY (sex determining region Y)-box 30 | SRY-box transcription factor 30, transcript variant 1 | Transcription factor SOX-30 (isoform a) | Sox30 protein type II | SOX30 variant 1 | SRY-box transcription factor 30 | Transcription factor SOX-30 | SRY-box 30 | SOX30_HUMAN

SOX30: A Potential Drug Target for Androsterone Deficiency and Cancer

SOX30, also known as SRY (sex determining region Y)-box 30, is a non-coding RNA molecule that is located in the gene cluster responsible for sex determination in many organisms, including humans. SOX30 plays a crucial role in the development and maintenance of male sexual characteristics, and is highly expressed in tests.

Recent studies have identified SOX30 as a potential drug target for treating androsterone deficiency, a common condition that affects male reproductive function, and testicular cancer. In addition, SOX30 has also been shown to be involved in the development of certain types of breast cancer, which further underscores its potential as a biomarker for this disease.

The SOX30 gene is located in the XY chromosome and has been implicated in the development and maintenance of male sexual characteristics. In humans, SOX30 is expressed in the testes, and its expression is highly correlated with the level of androgens, such as testosterone. When androgens are produced in the testes, they stimulate the development of sperm and the maintenance of male reproductive function.

In addition to its role in male reproductive function, SOX30 has also been shown to be involved in the development and maintenance of certain types of cancer. For example, studies have shown that SOX30 is highly expressed in breast tissue and is associated with the development of certain types of breast cancer. This suggests that SOX30 may be a useful biomarker for monitoring the progression of breast cancer.

In addition to its potential as a drug target and biomarker, SOX30 is also of interest as a potential therapeutic approach for androsterone deficiency and testicular cancer. Androsterone is a natural hormone that is produced by the tests and plays a crucial role in maintaining male reproductive function . In individuals with androsterone deficiency, testosterone levels become too low, which can lead to a range of negative health consequences, including decreased muscle mass, decreased bone density, and an increased risk of certain diseases.

SOX30 has been shown to be involved in the production and regulation of androsterone, which suggests that it may be a useful target for treating androsterone deficiency. Studies have shown that SOX30 can be activated by androgens, which suggests that it may be a good candidate for a drug that works by increasing the levels of androsterone in the body.

In addition to its potential as a drug target and biomarker, SOX30 is also of interest as a potential therapeutic approach for testicular cancer. Testicular cancer is a relatively rare type of cancer that is most common in children and young adults. It is often treated with chemotherapy, radiation therapy, or a combination of both, and the success of these treatments is often dependent on the presence of any remaining testicular tissue.

SOX30 has been shown to be involved in the development and maintenance of testicular tissue, which suggests that it may be a useful target for treatments that work to stop or slow the growth of cancerous testicular tissue. Studies have shown that SOX30 is highly expressed in testicular tissue and that its expression is associated with the development of certain types of testicular cancer. This suggests that SOX30 may be a useful biomarker for monitoring the progression of testicular cancer and the effectiveness of treatments.

In conclusion, SOX30 is a non-coding RNA molecule that is located in the gene cluster responsible for sex determination in many organisms, including humans. Its expression is highly correlated with the level of androgens and has been shown to be involved in the development and maintenance of male reproductive function and certain types of cancer. As a result, SOX30 is a potential drug target and biomarker for treating androsterone deficiency and testicular cancer. Further studies are needed to fully understand its potential as

Protein Name: SRY-box Transcription Factor 30

Functions: Acts as both a transcriptional activator and repressor (PubMed:10359848, PubMed:29739711). Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif (PubMed:10359848). Binds to its own promoter and activates its own transcription (By similarity). Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity). Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (PubMed:29739711). Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (PubMed:29739711)

The "SOX30 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SOX30 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110 | SP140 | SP140L | SP2 | SP2-AS1 | SP3 | SP3P | SP4 | SP5 | SP6 | SP7 | SP8 | SP9 | SPA17 | SPAAR | SPACA1 | SPACA3 | SPACA4 | SPACA5 | SPACA6 | SPACA6-AS1 | SPACA7 | SPACA9 | SPACDR | SPAG1 | SPAG11A | SPAG11B | SPAG16 | SPAG16-DT | SPAG17 | SPAG4 | SPAG5 | SPAG5-AS1 | SPAG6 | SPAG7 | SPAG8 | SPAG9 | SPAM1 | SPANXA1 | SPANXA2-OT1 | SPANXB1 | SPANXB2 | SPANXC | SPANXD | SPANXN1 | SPANXN2 | SPANXN3 | SPANXN4 | SPANXN5 | SPARC | SPARCL1 | SPART | SPART-AS1 | SPAST | SPATA1 | SPATA12 | SPATA13 | SPATA13-AS1 | SPATA16 | SPATA17 | SPATA18 | SPATA19 | SPATA2 | SPATA20 | SPATA20P1 | SPATA21 | SPATA22 | SPATA24 | SPATA25 | SPATA2L | SPATA3 | SPATA3-AS1 | SPATA31A1 | SPATA31A2 | SPATA31A3 | SPATA31A5 | SPATA31A6 | SPATA31A7 | SPATA31C1 | SPATA31C2 | SPATA31D1 | SPATA31D3 | SPATA31E1 | SPATA32 | SPATA33 | SPATA4 | SPATA41 | SPATA42 | SPATA45