SPACA9: A Potential Drug Target and Biomarker (G11092)

Target Name: SPACA9

NCBI ID: G11092

SPACA9

SPACA9: A Potential Drug Target and Biomarker

SPACA9, also known as Sperm Acrosome Associated 9, is a protein that is expressed in high levels in infertile sperm cells and plays a crucial role in the formation of spermatozoa. It is a member of the acrosome complex, a protein structure that is present in the head of each sperm cell and is thought to be involved in the mechanical forces that are required for fertilization.

Recent studies have identified SPACA9 as a potential drug target and biomarker for a range of reproductive and urologic conditions, including infertility, low sperm count, and testicular cancer.

One of the key reasons for the potential drug target status of SPACA9 is its involvement in the formation of spermatozoa. Spermatozoa are the sperm cells that are produced in the testes and are responsible for fertilization. In many cases, spermatozoa are not viable or contain genetic abnormalities that can result in infertility. The formation of spermatozoa is a critical process that requires the proper regulation of many genes, including those that are involved in cell division, differentiation, and survival. SPACA9 is thought to be involved in these processes and could be a useful target for drugs that are designed to promote the formation of healthy spermatozoa.

In addition to its role in sperm formation, SPACA9 has also been shown to be involved in the regulation of male reproductive function. In addition, it is expressed in high levels in infertile sperm cells and has been shown to be associated with the development of infertility in several animal models.

SPACA9 is also a potential biomarker for a range of reproductive and urologic conditions. For example, low sperm count, or oligospermia, is a common condition that is characterized by the presence of low levels of sperm in the semen. In many cases, the cause of oligospermia is not identified, and it can be a difficult condition to diagnose. SPACA9 has been shown to be expressed in the testes of individuals with low sperm count and has been shown to be involved in the formation of spermatozoa. This suggests that SPACA9 may be a useful biomarker for the diagnosis and treatment of oligospermia.

Another potential application of SPACA9 as a drug target is its role in the development of testicular cancer. Testicular cancer is a relatively common form of cancer that is most common in men, and it can be a difficult condition to diagnose. However, it is important to note that it is a relatively common condition that affects many men, and it is important to be able to diagnose and treat it as early as possible. SPACA9 has been shown to be expressed in the testes of individuals with testicular cancer and has been shown to be involved in the regulation of cell division and survival. This suggests that SPACA9 may be a useful target for the development of new treatments for testicular cancer.

In conclusion, SPACA9 is a protein that is involved in the formation of spermatozoa and has been shown to be involved in the regulation of male reproductive function. It is also a potential drug target and biomarker for a range of reproductive and urologic conditions, including infertility, low sperm count, and testicular cancer. Further research is needed to fully understand the role of SPACA9 in these processes and to develop new treatments for these conditions.

Protein Name: Sperm Acrosome Associated 9

Functions: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) of multiciliated respiratory cells and the distal singlet microtubules of monoflagellated spermatozoa. Forms both spirals and striations within ciliary microtubules. May stabilize the protofilaments to which they are bound

The "SPACA9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPACA9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets