HS6ST1: A Potential Drug Target and Biomarker (G9394)

Target Name: HS6ST1

NCBI ID: G9394

HS6ST1

HS6ST1: A Potential Drug Target and Biomarker

Introduction

High-throughput screening (HTS) technologies have revolutionized drug discovery, identifying potential drug targets and biomarkers. One of the most promising targets in the pipeline is the heat shock protein (HSP) HS6ST-1. HS6ST-1 is a key protein that can be expressed in a variety of cell types and has been shown to play a crucial role in various cellular processes. Its role in cellular stress response and its potential as a drug target make it an attractive target for researchers.

HS6ST-1: Structure and Function

HS6ST-1 is a member of the HSP family, which includes a variety of proteins that are involved in the regulation of protein expression and folding. These proteins are known as heat shock proteins (HSPs), named after their ability to withstand high temperatures. HSPs are highly conserved, with a conserved amino acid sequence that is often used as a target for drugs.

HS6ST-1 is a 26kDa protein that is expressed in a variety of cell types, including bacteria, yeast, plants, and animals. It is highly conserved, with a predicted amino acid sequence of N-伪-acetyl-L-glutamyl-L -alanine (N-伪-GLUT) Asp224, N-伪-acetyl-L-glutamyl-L-alanine (N-伪-GLUT) Asp89, N-伪-acetyl-L-glutamyl-L-alanine (N-伪 -GLUT) Asp162, N-伪-acetyl-L-glutamyl-L-alanine (N-伪-GLUT) Asp204, N-伪-acetyl-L-glutamyl-L-alanine (N-伪-GLUT) Asp208, N -伪-acetyl-L-glutamyl-L-alanine (N-伪-GLUT) Asp212, N-伪-acetyl-L-glutamyl-L-alanine (N-伪-GLUT) Asp221, and N-伪-acetyl- L-glutamyl-L-alanine (N-伪-GLUT) Asp224.

HS6ST-1 is involved in a variety of cellular processes, including the regulation of protein expression and stress response. One of its well-documented functions is its role in the regulation of protein expression in response to stress. When cells are exposed to stress, such as heat or radiation, HS6ST-1 is shown to play a key role in the adaptation of these cells to the stress environment.

HS6ST-1 has also been shown to play a role in the regulation of protein folding and stability. It has been shown to interact with a variety of protein partners, including heat shock factors (HSFs), which are proteins that are involved in the regulation of protein expression and stability. These interactions suggest that HS6ST-1 may be a critical regulator of protein expression and folding in response to stress.

Drug Targeting

The potential drug targeting of HS6ST-1 is based on its role in the regulation of protein expression and stress response. Drugs that can modulate HS6ST-1 activity may have a variety of therapeutic effects, including the inhibition of cellular stress response and the regulation of protein expression.

One approach to drug targeting

Protein Name: Heparan Sulfate 6-O-sulfotransferase 1

Functions: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid

The "HS6ST1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HS6ST1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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