Target Name: HSFY1
NCBI ID: G86614
Review Report on HSFY1 Target / Biomarker Content of Review Report on HSFY1 Target / Biomarker
HSFY1
Other Name(s): Heat shock transcription factor, Y-linked | heat shock transcription factor Y-linked 1 | Heat shock transcription factor, Y-linked (isoform 1) | Heat shock transcription factor, Y-linked (isoform 2) | HSFY2 | HSFY1 variant 1 | OTTHUMP00000038978 | HSFY1_HUMAN | OTTHUMP00000038977 | HSF2-like | Heat shock transcription factor 2-like protein | Heat shock transcription factor Y-linked 1, transcript variant 1 | Heat shock transcription factor Y-linked 1, transcript variant 2 | HSF2L | heat shock transcription factor 2-like protein | HSFY | HSFY1 variant 2

HSFY1: A Non-Coding RNA Molecule in Stress Response

Heat shock transcription factor (HSFY1) is a protein that plays a crucial role in the regulation of gene expression in response to thermal stress. HSFY1 is a non-coding RNA molecule that is expressed in a variety of tissues and cells, including muscle, heart , and brain. It is highly conserved and has a conserved domain that is similar to other transcription factors, including the DNA binding domain where transcription factors bind. The function of HSFY1 under heat stress has been extensively studied, especially its role in stress response.

Biological functions of HSFY1

The role of HSFY1 in stress response is mainly reflected at the transcription level. Under heat stress conditions, HSFY1 can bind to DNA and initiate gene transcription by binding to specific sequences on the DNA. Studies have shown that HSFY1 plays a role in promoting gene expression in stress responses, especially in the heat shock element (HSFY1-stress element).

HSFY1-stress element

The stress element of HSFY1 is a non-coding RNA located at the 3' end of the HSFY1 gene, including a conserved DNA binding domain and a conserved transcription factor binding domain. HSFY1-stress element is a series of conserved base pairs from the N-terminus to the C-terminus of HSFY1, which can bind to DNA and play a key role in stress response.

Drug targets for HSFY1

Because HSFY1 plays an important role in stress response, it is widely considered as a potential drug target. Some studies have shown that HSFY1 can participate in a variety of physiological processes, including cell proliferation, apoptosis, metabolism and signal transduction, by regulating gene expression.

Biological significance of HSFY1

The role of HSFY1 in stress responses and its importance as a drug target have been extensively studied. As an important transcription factor, HSFY1 plays a key role in stress response and provides an important theoretical basis for studying biological processes under heat stress.

in conclusion

HSFY1 is a protein that plays an important role in stress response. The stress element of HSFY1 plays a key role in the heat shock response, and HSFY1 itself can also be used as a drug target. Future research will continue to further study the role of HSFY1 in stress response and drug treatment, providing new ideas and methods for the treatment of various heat stress-related diseases.

Protein Name: Heat Shock Transcription Factor Y-linked 1

The "HSFY1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HSFY1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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