NCMAP: Key Protein in Myelination and Pain Perception (G400746)

Target Name: NCMAP

NCBI ID: G400746

NCMAP

NCMAP: Key Protein in Myelination and Pain Perception

Myelination is a critical part of the central nervous system (CNS) development and function. It plays a vital role in the development and maintenance of neural circuits, and is also involved in the regulation of various physiological processes in the CNS, including pain perception and neurotransmitter release. Myelination is composed of several protein species, including non-compact myelin associated protein (NCMAP), which is a key protein involved in the development and maintenance of the myelin sheath surrounding the neurons.

NCMAP is a transmembrane protein that is expressed in a variety of neural tissues, including the brain, spinal cord, and peripheral nerves. It is one of the largest proteins involved in myelination, and is responsible for several key functions, including the maintenance of the myelin sheath, the regulation of neurotransmitter release, and the contribution to pain perception and neurotransmission.

Despite the importance of NCMAP in myelination, much is still not known about its function and the underlying mechanisms that regulate its activity. This is why NCMAP is an attractive drug target and a potential biomarker for various neurological and psychiatric disorders.

NCMAP and Myelination

NCMAP is a protein that is composed of four intracellular domains: a N-terminus, a transmembrane region, a cytoplasmic-terminal region and a C-terminus. The N-terminus of NCMAP is involved in the interaction with several intracellular signaling pathways, including the TGF-β pathway. The transmembrane region of NCMAP is responsible for its ability to interact with various intracellular signaling pathways, including the ERK pathway and the PI3K/Akt pathway. The cytoplasmic-terminal region of NCMAP is involved in the interaction with several intracellular signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway. The C-terminus of NCMAP is involved in the interaction with several intracellular signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway.

NCMAP plays a key role in the development and maintenance of the myelin sheath surrounding the neurons. The myelin sheath is a specialized protein that is responsible for providing mechanical stability to the neuron and for participating in the regulation of pain perception and neurotransmission. NCMAP is involved in the regulation of several key events that are involved in myelination, including the regulation of neurotransmitter release, the maintenance of the myelin sheath, and the contribution to pain perception and neurotransmission.

NCMAP and Neurotransmission

NCMAP is involved in the regulation of neurotransmission by contributing to the release of neurotransmitters from the axon terminal of neurons. It does this by participating in the regulation of the pre-synaptic release of neurotransmitters, as well as the regulation of the post-synaptic reception of these neurotransmitters by the target cells.

NCMAP is also involved in the regulation of neurotransmission by contributing to the transmission of pain signals from the CNS to the peripheral nervous system. It does this by participating in the regulation of the release of pain-related neurotransmitters from the axon terminal of neurons and the uptake of these neurotransmitters by the target cells in the peripheral nervous system.

NCMAP and Pain Perception

Pain perception is a critical aspect of neurotransmission, and NCMAP is involved in its regulation. It does this by contributing to the regulation of the release of pain-related neurotransmitters from the axon terminal of neurons, which is involved in the sensation of pain. Additionally , NCMAP is involved in the regulation of the sensitivity

Protein Name: Non-compact Myelin Associated Protein

Functions: Plays a role in myelin formation

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•   general information;
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•   the target screening and validation;
•   expression level;
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•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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