NCKAP1: Potential Therapeutic Targets and Biomarkers (G10787)

Target Name: NCKAP1

NCBI ID: G10787

NCKAP1

NCKAP1: Potential Therapeutic Targets and Biomarkers

NCKAP1 (NCK associated protein 1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and skeletal muscles. It is a key regulator of the myosin ATPase complex, which is responsible for generating force and power in muscle fibers. NCKAP1 has also been shown to play a role in a variety of cellular processes, including cell signaling, cell division, and neurodegeneration.

Recent studies have suggested that NCKAP1 may be a drug target or biomarker for a variety of conditions, including cancer, neurodegenerative diseases, and muscle-related injuries. This is because NCKAP1 has been shown to be involved in a variety of cellular processes that are often disrupted in these conditions, and because it has been shown to play a negative role in the development of these conditions.

One potential mechanism by which NCKAP1 may be involved in cancer is by regulating the growth and survival of cancer cells. NCKAP1 has been shown to promote the growth and survival of a variety of cancer cells, including breast, lung, and ovarian cancer cells. This may be because NCKAP1 helps to regulate the cell cycle, which is the process by which cells grow and divide.

Another potential mechanism by which NCKAP1 may be involved in neurodegenerative diseases is by contributing to the development and progression of these conditions. NCKAP1 has been shown to play a role in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This may be because NCKAP1 helps to regulate the production of beta-amyloid, a protein that is thought to contribute to the development of these conditions.

In addition to its potential role in cancer and neurodegenerative diseases, NCKAP1 has also been suggested as a potential biomarker for a variety of conditions. For example, some studies have suggested that NCKAP1 may be involved in the development of muscle-related injuries, such as muscle strain and muscle failure. This may be because NCKAP1 helps to regulate the use and regeneration of muscle fibers, and may be involved in the repair process following muscle injury.

Overall, while more research is needed, it is clear that NCKAP1 is involved in a variety of cellular processes that are important for the health and function of the body. As such, it is a potential drug target or biomarker for a variety of conditions, including cancer, neurodegenerative diseases, and muscle-related injuries.

Protein Name: NCK Associated Protein 1

Functions: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes

The "NCKAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NCKAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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