Target Name: NCAN
NCBI ID: G1463
Review Report on NCAN Target / Biomarker Content of Review Report on NCAN Target / Biomarker
NCAN
Other Name(s): Chondroitin sulfate proteoglycan 3 | neurocan | Chondroitin sulfate proteoglycan 3 (neurocan) | Neurocan proteoglycan | chondroitin sulfate proteoglycan 3 (neurocan) | Neurocan | Neurocan core protein | CSPG3 | neurocan proteoglycan | NCAN_HUMAN | FLJ44681

NCAN: A Protein Involved in Tissue Development, Wound Healing and Inflammation

NCAN (Chondroitin sulfate proteoglycan 3) is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is a member of the chondroitin sulfate proteoglycan (CSG) family, which is a group of proteins that play a role in the structure and function of extracellular matrix (ECM) components.

NCAN has been shown to be involved in a number of cellular processes that are important for tissue development, wound healing, and inflammation. It is involved in the regulation of cell proliferation, differentiation, and survival, as well as in the production of ECM components such as collagen and hyaluronic acid.

NCAN has also been shown to be involved in the regulation of signaling pathways that are important for tissue growth and development. For example, NCAN has been shown to play a role in the Wnt signaling pathway, a pathway that is important for the development and maintenance of tissues during embryonic development.

In addition to its role in tissue development and signaling pathways, NCAN has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function, and has been shown to produce pro-inflammatory cytokines in response to certain stimuli.

Given its involvement in a number of important cellular processes, NCAN has been considered as a potential drug target or biomarker. There is ongoing research into the use of small molecules and other compounds to modulate the activity of NCAN, with the goal of developing treatments for a variety of diseases.

One approach to targeting NCAN is to use small molecules that can modulate the activity of NCAN. For example, researchers have developed a number of small molecules that can inhibit the activity of NCAN, such as inhibitors of the enzyme chondroitin sulfate synthetase (CSS), which is responsible for the production of chondroitin sulfate in the ECM.

Another approach to targeting NCAN is to use antibodies that can specifically bind to NCAN and prevent it from participating in its cellular functions. Researchers have developed antibodies that can be used to treat a variety of diseases, including cancer,Wound healing, and autoimmune disorders.

In addition to its potential use as a drug or biomarker, NCAN has also been shown to be an attractive target for research into the regulation of cellular processes. Its involvement in a number of important cellular processes makes it an attractive study system for researchers looking to understand the mechanisms that regulate cell behavior and function.

Overall, NCAN is a protein that has been shown to be involved in a number of important cellular processes, including tissue development, wound healing, and inflammation. Its potential as a drug target or biomarker makes it an attractive study system for researchers looking to understand the mechanisms that regulate cell behavior and function. Further research is needed to fully understand the role of NCAN in these processes and its potential as a therapeutic agent.

Protein Name: Neurocan

Functions: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid

The "NCAN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NCAN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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