Target Name: ENTPD4
NCBI ID: G9583
Review Report on ENTPD4 Target / Biomarker Content of Review Report on ENTPD4 Target / Biomarker
ENTPD4
Other Name(s): Golgi UDPase | LAP70 | Ectonucleoside triphosphate diphosphohydrolase 4 (isoform a) | ENTP4_HUMAN | guanosine-diphosphatase like protein | Ectonucleoside triphosphate diphosphohydrolase 4 | golgi luminal UDPase | uridine-diphosphatase | LYSAL1 | lysosomal apyrase-like 1 | NTPDase 4 | ectonucleoside triphosphate diphosphohydrolase 4 | UDPase | NTPDase-4 | lysosomal apyrase-like protein of 70 kDa | LALP70 | ENTPD4 variant 1 | Uridine-diphosphatase | Ectonucleoside triphosphate diphosphohydrolase 4, transcript variant 1 | KIAA0392 | Lysosomal apyrase-like protein of 70 kDa

ENTPD4: Key Enzyme for Cellular Processes

ENTPD4 (Endoplasmic Reticulum-Proteinase 4) is a protein that is expressed in most tissues of the body. It is a key enzyme that is involved in the degradation of proteins, which is a critical process in the cell. ENTPD4 is also known as Golgi UDPase because it is an enzyme that is present in the Golgi system, which is a network of organelles that are responsible for the proper sorting and delivery of proteins in the cell.

ENTPD4 is widely expressed in many different tissues and cells, including the brain, pancreas, and heart. It is also highly expressed in the placenta, which is a vital organ that supports the growth and development of fetal tissues. ENTPD4 is involved in the regulation of a wide range of cellular processes, including cell signaling, DNA replication, and protein degradation.

One of the key functions of ENTPD4 is its role in the degradation of proteins that are no longer needed or that are damaged. This is important for maintaining the integrity of the cell and for ensuring that unnecessary or harmful proteins are not present in the cell. ENTPD4 helps to break down proteins that are decommissioned, damaged or misfolded, which allows the cell to remove them and to generate new ones.

ENTPD4 is also involved in the regulation of the cytoskeleton, which is the structure that gives shape to the cell. The cytoskeleton is made up of a complex network of proteins that help to keep the cell in a proper shape and to provide support for the various organelles that are present in the cell. ENTPD4 is involved in the breakdown of the cytoskeleton, which allows the cell to change its shape and to move in response to various stimuli.

ENTPD4 is also involved in the regulation of cell signaling, which is the process by which cells communicate with one another and with their environment. Signalings are important for the proper functioning of the cell and for ensuring that cells respond to various stimuli. ENTPD4 is involved in the degradation of proteins that are involved in signaling, which allows the cell to remove unnecessary or harmful signals and to generate new ones.

ENTPD4 is also involved in the regulation of DNA replication, which is the process by which a cell makes copies of its DNA. DNA replication is important for the continuation of the cell's genetic heritage and for ensuring that the cell is able to divide and replicate its tissues. ENTPD4 is involved in the regulation of DNA replication by breaking down the DNA double helix, which allows the cell to separate the two copies of its DNA.

ENTPD4 is also involved in the regulation of protein degradation, which is the process by which cells remove unnecessary or damaged proteins. This is important for maintaining the integrity of the cell and for ensuring that cells are able to function properly. ENTPD4 is involved in the Regulation of protein degradation by breaking down the proteins that are no longer needed or that are damaged, which allows the cell to remove them and to generate new ones.

In conclusion, ENTPD4 is a key enzyme that is involved in the regulation of a wide range of cellular processes. It is expressed in most tissues of the body and is involved in the degradation of proteins, cytoskeleton, cell signaling, DNA replication, and protein degradation. As a result, ENTPD4 is a potential drug target and may be useful as a biomarker for various diseases.

Protein Name: Ectonucleoside Triphosphate Diphosphohydrolase 4

Functions: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates (PubMed:10858452, PubMed:9556635). Preferentially activated by Ca(2+) over Mg(2+) (PubMed:10858452)

The "ENTPD4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENTPD4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ENTPD5 | ENTPD6 | ENTPD7 | ENTPD8 | ENTR1 | ENTREP1 | ENTREP2 | ENTREP3 | env | ENY2 | EOGT | EOLA1 | EOLA1-DT | EOLA2 | EOLA2-DT | EOMES | EP300 | EP300-AS1 | EP400 | EP400P1 | EPAS1 | EPB41 | EPB41L1 | EPB41L1-AS1 | EPB41L2 | EPB41L3 | EPB41L4A | EPB41L4A-AS1 | EPB41L4A-DT | EPB41L4B | EPB41L5 | EPB42 | EPC1 | EPC2 | EPCAM | EPCAM-DT | EPDR1 | EPG5 | EPGN | EPHA1 | EPHA1-AS1 | EPHA10 | EPHA2 | EPHA2-AS1 | EPHA3 | EPHA4 | EPHA5 | EPHA5-AS1 | EPHA6 | EPHA7 | EPHA8 | EPHB1 | EPHB2 | EPHB3 | EPHB4 | EPHB6 | Ephrin Receptor | EPHX1 | EPHX2 | EPHX3 | EPHX4 | EPIC1 | EPIST | Epithelial Sodium Channel (ENaC) | EPM2A | EPM2A-DT | EPM2AIP1 | EPN1 | EPN2 | EPN3 | EPO | EPOP | EPOR | Epoxide Hydrolase | EPPIN | EPPK1 | EPRS1 | EPS15 | EPS15L1 | EPS8 | EPS8L1 | EPS8L2 | EPS8L3 | EPSTI1 | EPX | EPYC | EQTN | ER Membrane Protein Complex | ERAL1 | ERAP1 | ERAP2 | ERAS | ERBB2 | ERBB3 | ERBB4 | ERBIN | ERC1 | ERC2 | ERC2-IT1 | ERCC1