SPAG17: A Potential Drug Target Or Biomarker (G200162)

Target Name: SPAG17

NCBI ID: G200162

SPAG17

SPAG17: A Potential Drug Target Or Biomarker

SPAG17, also known as sperm-associated antigen 17, is a protein that is expressed in high levels in the testes and other body tissues. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased temperatures, such as those experienced during the process of sperm production.

SPAG17 is of particular interest as a potential drug target or biomarker due to its involvement in several important biological processes. One of its key functions is to help regulate the entry of immune cells into the testes, which are responsible for maintaining the health and integrity of the male reproductive system.

In addition to its role in immune regulation, SPAG17 is also involved in several other biological processes that are important for human health. For example, it has been shown to play a key role in the development and maintenance of normal brain function, as well as in the regulation of cellular signaling processes that are involved in a wide range of biological processes, including cell growth, differentiation, and inflammation.

SPAG17 is also of particular interest as a potential drug target because it is known to be involved in the development of certain types of cancer. For example, studies have shown that high levels of SPAG17 are associated with the development of certain types of breast cancer, as well as with the progression of certain types of prostate cancer.

In addition to its potential as a drug target or biomarker, SPAG17 is also of interest as a potential vaccine candidate. Because it is expressed in high levels in a variety of body tissues, it could be used as a potential vaccine ingredient to stimulate an immune response in the body against a range of pathogens.

Overall, SPAG17 is a protein that is of great interest due to its involvement in several important biological processes, including immune regulation, brain function, and cancer development. As a result, it is a potential drug target or biomarker that could be used to treat a wide range of diseases and conditions.

Protein Name: Sperm Associated Antigen 17

Functions: Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts (By similarity). Essential for normal spermatogenesis and male fertility (By similarity). Required for normal manchette structure, transport of proteins along the manchette microtubules and formation of the sperm head and flagellum (By similarity). Essential for sperm flagellum development and proper assembly of the respiratory motile cilia central pair apparatus, but not the brain ependymal cilia (By similarity)

The "SPAG17 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPAG17 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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