DRAM2: Regulating Autophagy and Cellular Stress (G128338)

Target Name: DRAM2

NCBI ID: G128338

DRAM2

DRAM2: Regulating Autophagy and Cellular Stress

DRAM2, also known as DNA damage regulated autophagy modulator 2, is a protein that plays a crucial role in the regulation of autophagy, a process that is essential for the survival and growth of all living organisms. Autophagy is the process by which cells break down and recycle damaged or unnecessary cellular components, thereby maintaining cellular homeostasis and preventing the buildup of harmful substances that can harm the cell.DRAM2, which was first identified in 2012, is a non-coding RNA molecule that is regulated by DNA damage.

DRAM2 is a key regulator of autophagy, and it is involved in the formation of damaged cellular organelles, such as damaged mitochondria and damaged autophagos. It is also involved in the regulation of cellular stress responses, which are critical for maintaining cellular homeostasis in the face of environmental stressors, such as those caused by toxins, radiation, or metabolic changes.

DRAM2 is expressed in most tissues and cells of the body, and it is highly conserved across different species. It is also a good candidate drug target, as it has been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

One of the key functions of DRAM2 is its role in the regulation of autophagy. Autophagy is a highly dynamic process that is essential for the survival and growth of all living organisms. It is during autophagy that cells break down and recycle damaged or unnecessary cellular components, such as misfolded proteins, damaged organelles, and other damaged cellular components.

DRAM2 is involved in the regulation of autophagy by promoting the formation of damaged cellular organelles, such as damaged mitochondria and damaged autophagos. It does this by regulating the activity of several key genes that are involved in the formation of these damaged cellular organelles.

For example, DRAM2 has been shown to regulate the activity of the gene HDAC1, which encodes a protein that is involved in the inhibition of the histone acetylation process. This process is important for the regulation of cellular stress responses and for the formation of damaged cellular organelles.

DRAM2 is also involved in the regulation of autophagy by regulating the activity of the gene APC1, which encodes a protein that is involved in the activation of autophagy.

In addition to its role in the regulation of autophagy, DRAM2 is also involved in the regulation of cellular stress responses. It does this by regulating the activity of several key genes that are involved in the regulation of cellular stress responses, including the gene NLRP1, which encodes a protein that is involved in the formation of a protein complex that is involved in the regulation of cellular stress responses.

DRAM2 is also involved in the regulation of cellular homeostasis, as it is regulated by DNA damage. This means that its activity can be regulated by the presence of DNA damage, such as that caused by exposure to radiation or other toxic substances.

In conclusion, DRAM2 is a protein that plays a crucial role in the regulation of autophagy, as well as cellular stress responses and cellular homeostasis. It is a good candidate drug target and may be a useful therapeutic target for a variety of diseases. Further research is needed to fully understand the role of DRAM2 in these processes and to develop effective treatments based on its activity.

Protein Name: DNA Damage Regulated Autophagy Modulator 2

Functions: Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1

The "DRAM2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DRAM2 comprehensively, including but not limited to:
•   general information;
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•   the target screening and validation;
•   expression level;
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•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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