GATA2: A Key Regulator of Angiogenesis and Cellular Processes

Target Name: GATA2

NCBI ID: G2624

GATA2

GATA2: A Key Regulator of Angiogenesis and Cellular Processes

GATA2 (Endothelial transcription factor GATA-2 (isoform 2)) is a protein that plays a crucial role in the regulation of cell growth, differentiation, and survival. It is a member of the GATA family of transcription factors, which are known for their ability to control gene expression in response to various signaling cues. GATA2 is widely expressed in various tissues and cells, including the brain, heart, kidneys, and intestines, and is involved in the regulation of a wide range of biological processes, including cell proliferation , migration, and differentiation.

GATA2 is a key regulator of angiogenesis, which is the process by which new blood vessels grow and form in the body. During angiogenesis, GATA2 is involved in the regulation of cell proliferation and differentiation, as well as the regulation of blood vessel morphology and function..

GATA2 is also involved in the regulation of cell survival and stress resistance. It has been shown to play a role in the regulation of cell cycle progression, apoptosis, and autophagy, as well as in the regulation of cellular stress responses.

GATA2 has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function and the regulation of inflammatory responses.

GATA2 is a potential drug target and may be a useful biomarker for the diagnosis and treatment of various diseases. For example, GATA2 has been shown to be involved in the regulation of cancer cell growth and has been shown to be a potential target for inhibitors of angiogenesis. Additionally, GATA2 has been shown to be involved in the regulation of cardiovascular disease, and may be a potential target for therapies aimed at treating heart failure and other cardiovascular conditions.

GATA2 is a complex protein that is involved in a wide range of important biological processes in the body. It is a potential drug target and may be a useful biomarker for the diagnosis and treatment of various diseases. Further research is needed to fully understand the role of GATA2 in biology and to develop effective therapies based on its properties.

Protein Name: GATA Binding Protein 2

Functions: Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'

The "GATA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GATA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets