GASK1A: A Potential Drug Target and Biomarker (G729085)

Target Name: GASK1A

NCBI ID: G729085

GASK1A

GASK1A: A Potential Drug Target and Biomarker

GASK1A, also known as Protein FAM198A, is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug may have significant implications for the treatment of these diseases.

GASK1A is a transmembrane protein that is expressed in various tissues and cells throughout the body. It is characterized by a unique fold structure that is composed of a conserved N-terminal region, a transmembrane region, and a C-terminal region. The N-terminal region contains a putative N-acetylation site, which has been implicated in the protein's stability and functions. The transmembrane region is made up of four伪-helices and is known for its unique farnesylated cysteine residue, which is known to play a role in the regulation of the protein's stability and localization. The C-terminal region contains a conserved Glu-Pro-Glu loop and a putative Glu-Tyr-Glu loop, both of which may be involved in the regulation of the protein's activity.

GASK1A has been shown to play a role in various physiological processes, including cell signaling, cell adhesion, and tissue repair. It has also been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that GASK1A is overexpressed in various types of cancer, including breast, lung, and colorectal cancer. It has also been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Additionally, GASK1A has been implicated in the development and progression of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

GASK1A has also been shown to be a potential drug target. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug may have significant implications for the treatment of these diseases. For example, studies have shown that GASK1A can be targeted by small molecules, including inhibitors of the protein's N-acetylation site and the Glu-Tyr-Glu loop. Additionally, GASK1A can be targeted by antibodies that recognize its unique fold structure.

In addition to its potential as a drug target, GASK1A is also a potential biomarker. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a biomarker may have significant implications for the diagnosis and treatment of various diseases. For example, studies have shown that GASK1A can be used as a diagnostic marker for cancer, including breast, lung, and colorectal cancer. Additionally, GASK1A has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Its potential as a biomarker may have significant implications for the diagnosis and treatment of these diseases.

Overall, GASK1A is a protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug or biomarker may have significant implications for the treatment of these diseases. Further research is needed to fully understand its role in the development and progression of these diseases, and to determine its potential as a drug or biomarker.

Protein Name: Golgi Associated Kinase 1A

The "GASK1A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GASK1A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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