GCFC2 as A Potential Drug Target and Biomarker (G6936)

Target Name: GCFC2

NCBI ID: G6936

GCFC2

GCFC2 as A Potential Drug Target and Biomarker

Gene expression control complex 2 (GCFC2) is a non-coding RNA molecule that plays a crucial role in regulating gene expression in various organisms, including humans. GCFC2 is a large complex component of the gene expression machinery and is involved in the regulation of gene expression, DNA replication, and other cellular processes. The identification and characterization of GCFC2 as a potential drug target or biomarker has significant implications for the development of new therapeutic strategies for various diseases.

GCFC2 Structure and Function

GCFC2 is a large non-coding RNA molecule that has a typical length of approximately 1,900 nucleotides. It is composed of several subunits, including the N-terminal alpha-helix, the C-terminal RNA-binding protein (RBP), and the core region. The N-terminal alpha-helix is 鈥嬧?媡he most prominent structural feature of GCFC2 and is involved in the formation of a distinct domain that is distinct from the other subunits.

The C-terminal region of GCFC2 is characterized by a series of functional domains, including a double-stranded RNA-binding domain (DSBD), a single-stranded RNA-binding domain (SSBD), and a T-loop region. The DSBD and SSBD are involved in the regulation of gene expression and are considered to be critical for the function of GCFC2. The T-loop region is involved in the stability of the GCFC2 complex and is thought to play a role in the regulation of DNA replication.

GCFC2 is involved in several cellular processes, including gene expression, DNA replication, and cell growth. It is well established that GCFC2 plays a role in regulating gene expression by binding to specific DNA sequences and affecting the activity of transcription factors. For example, studies have shown that GCFC2 can bind to the core region of the transcription factor p53 and that this binding is necessary for the regulation of p53-mediated gene expression.

GCFC2 is also involved in the regulation of DNA replication. Research shows that GCFC2 plays a role in the regulation of DNA replication by binding to the enzyme responsible for DNA replication, called DNA polymerase. This binding is thought to ensure that GCFC2 is present at the site of DNA replication and that it can influence the efficiency of DNA replication.

GCFC2 is also involved in the regulation of cell growth. Studies have shown that GCFC2 plays a role in the regulation of cell growth by controlling the activity of the oncogene WAF-1. WAF-1 is a transcription factor that is involved in the regulation of cell growth and has been implicated in the development of many diseases, including cancer.

GCFC2 as a Drug Target

The identification of GCFC2 as a potential drug target has significant implications for the development of new therapeutic strategies for various diseases. One of the main advantages of GCFC2 as a drug target is its widespread involvement in various cellular processes, which makes it difficult to identify specific compounds that can interact with it.

Studies have shown that GCFC2 can be targeted with small molecules, peptides, and other types of compounds. Many of these compounds have been shown to have activity against various diseases, including cancer, neurodegenerative diseases, and respiratory diseases. For example, studies have shown that inhibitors of the oncogene transforming growth factor (TGF-1), which is a potent regulator of GCFC2, have significant activity against the development of cancer.

In addition to its potential as a drug target, GCFC2 is also an attractive biomarker for the diagnosis and assessment of various diseases. The regulation of GCFC2 by oncogenes is a well-established feature of cancer development, and the levels of GCFC2 have been shown to be altered in many types of cancer. Therefore, the measurement of GCFC2 levels in cancer cells or tissues could be

Protein Name: GC-rich Sequence DNA-binding Factor 2

Functions: Involved in pre-mRNA splicing through regulating spliceosome C complex formation (PubMed:24304693). May play a role during late-stage splicing events and turnover of excised introns (PubMed:24304693)

The "GCFC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GCFC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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