GAS6-AS1: A Potential Drug Target and Biomarker (G650669)
GAS6-AS1: A Potential Drug Target and Biomarker
GAS6-AS1, also known as GAS6 antisense RNA 1, is a non-coding RNA molecule that has been identified as a potential drug target and biomarker in various diseases, including cancer. Its unique structure and function make it an attractive target for researchers to study and develop new treatments.
GAS6-AS1 is a small RNA molecule that is approximately 200 nucleotides long. It is produced by RNA-mediated cleavage reaction and is transcribed from the RNA encoding the gene. GAS6-AS1 is an antisense RNA whose 5'-end interacts with the 3'-end of a GAS6 protein to form a GAS6-AS1-GAS6 structure. GAS6 is a conserved protein with conserved amino acid sequences in different organisms. The 3'-end of GAS6-AS1 contains a cap structure. The methyl group (CH3) in the cap structure can form a hydrogen bond with the carbonyl group (C=O) on the Glu215 residue of the GAS6 protein, thereby enhancing the GAS6-AS1-GAS6 structure. stability.
The function of GAS6-AS1 is mainly manifested in tumorigenesis and progression. Studies have shown that GAS6-AS1 is up-regulated in a variety of tumors, including lung cancer, liver cancer, breast cancer, etc. The expression level of GAS6-AS1 is positively correlated with tumor indicators such as tumor invasion ability, growth rate, and survival time. In addition, GAS6-AS1 is also associated with apoptosis and proliferation of tumor cells. Studies have shown that the expression level of GAS6-AS1 can regulate the proliferation of tumor cells by regulating cell cycle, inducing apoptosis and other mechanisms.
Because GAS6-AS1 plays an important role in tumorigenesis and progression, it is regarded as a potential drug target. The expression level of GAS6-AS1 can be regulated through multiple pathways, including regulating gene expression, epigenetic modification, etc. These regulatory mechanisms make GAS6-AS1 a potential drug target.
In addition, GAS6-AS1 can also serve as a biomarker. The expression level of GAS6-AS1 in tumor patients is positively correlated with tumor indicators such as tumor invasion ability, growth rate, and survival period. Therefore, GAS6-AS1 can be used as a tumor biomarker. By detecting the expression level of GAS6-AS1, doctors can evaluate the condition of tumor patients and provide patients with more accurate diagnosis and treatment plans.
GAS6-AS1, as a non-coding RNA molecule, has unique structure and function. By studying GAS6-AS1, we can gain a deeper understanding of the regulatory mechanism of RNA splicing reactions and provide new ideas and methods for tumor treatment. At the same time, GAS6-AS1, as a potential drug target and biomarker, also has broad application prospects. With the deepening of research, GAS6-AS1 will play a more important role in tumor treatment.
Protein Name: GAS6 Antisense RNA 1
The "GAS6-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GAS6-AS1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
GAS7 | GAS8 | GAS8-AS1 | GASAL1 | GASK1A | GASK1B | GASK1B-AS1 | GAST | GATA1 | GATA2 | GATA2-AS1 | GATA3 | GATA3-AS1 | GATA4 | GATA5 | GATA6 | GATA6-AS1 | GATAD1 | GATAD2A | GATAD2B | GATB | GATC | GATD1 | GATD1-DT | GATD3 | GATM | GATOR1 Complex | GAU1 | GBA1 | GBA2 | GBA3 | GBAP1 | GBE1 | GBF1 | GBGT1 | GBP1 | GBP1P1 | GBP2 | GBP3 | GBP4 | GBP5 | GBP6 | GBP7 | GBX1 | GBX2 | GC | GCA | GCAT | GCC1 | GCC2 | GCC2-AS1 | GCDH | GCFC2 | GCG | GCGR | GCH1 | GCHFR | GCK | GCKR | GCLC | GCLM | GCM1 | GCM2 | GCN1 | GCNA | GCNT1 | GCNT1P3 | GCNT2 | GCNT3 | GCNT4 | GCNT7 | GCOM1 | GCSAM | GCSAML | GCSAML-AS1 | GCSH | GCSHP3 | GCSIR | GDA | GDAP1 | GDAP1L1 | GDAP2 | GDE1 | GDF1 | GDF10 | GDF11 | GDF15 | GDF2 | GDF3 | GDF5 | GDF6 | GDF7 | GDF9 | GDI1 | GDI2 | GDI2P1 | GDNF | GDNF Family Receptor alpha | GDNF-AS1 | GDPD1
