Target Name: GBGT1
NCBI ID: G26301
Review Report on GBGT1 Target / Biomarker Content of Review Report on GBGT1 Target / Biomarker
GBGT1
Other Name(s): OTTHUMP00000022447 | GBGT1_HUMAN | Forssman synthetase | GBGT1 variant 1 | OTTHUMP00000022448 | RP11-326L24.6 | UNQ2513 | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (isoform 1) | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 | Forssman glycolipid synthase-like protein | OTTHUMP00000022446 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) | FS | MGC44848 | Forssman glycolipid synthetase (FS) | forssman glycolipid synthase-like protein | A3GALNT | Forssman blood group | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group), transcript variant 1

GBGT1: A Glycopharmacutical with Potential as A Drug Target

Glycopharmacuticals (GBGT1) are a class of drugs that are designed to selectively target specific proteins involved in cellular processes. One of the most promising areas of research in the field of Glycopharmacuticals is the study of their potential as drug targets. GBGT1 is a glycopharmacutical that has been shown to be involved in a variety of cellular processes, including cell signaling, angiogenesis, and inflammation. As a result, GBGT1 has potential as a drug target for a variety of diseases.

GBGT1 is a protein that is expressed in a variety of tissues and cells, including the brain, heart, and blood vessels. It is involved in the regulation of cell signaling pathways, including those involved in neurotransmitter signaling, cell adhesion, and cell signaling. GBGT1 has been shown to play a role in the regulation of neurotransmitter signaling by binding to the neurotransmitter GABA and interacting with the G protein-coupled receptor GBPR2.

In addition to its role in neurotransmitter signaling, GBGT1 is also involved in the regulation of angiogenesis, the process by which new blood vessels are formed. GBGT1 has been shown to play a role in the regulation of angiogenesis by binding to the transcription factor FGF1 and interacting with the protein PDGF.

GBGT1 is also involved in the regulation of inflammation, including the regulation of the immune response and the regulation of inflammation-related pain. GBGT1 has been shown to play a role in the regulation of inflammation by binding to the transcription factor NF-kappa-B and interacting with the protein TNF-伪.

Due to its involvement in a variety of cellular processes, GBGT1 has been identified as a potential drug target for a variety of diseases. For example, GBGT1 has been shown to be involved in the regulation of neurotransmission in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It has also been shown to be involved in the regulation of angiogenesis in diseases such as cancer, where it has been shown to promote the formation of new blood vessels.

In addition to its potential as a drug target, GBGT1 is also a valuable biomarker for a variety of diseases. For example, GBGT1 has been shown to be involved in the regulation of neurotransmission in various psychiatric diseases, including depression and anxiety. It has also been shown to be involved in the regulation of angiogenesis in diseases such as cancer and neurodegenerative diseases.

In conclusion, GBGT1 is a protein that is involved in a variety of cellular processes, including cell signaling, angiogenesis, and inflammation. As a result, it has potential as a drug target for a variety of diseases. Further research is needed to fully understand the role of GBGT1 in disease and to develop safe and effective drugs that target this protein.

Protein Name: Globoside Alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS Blood Group)

Functions: Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) (PubMed:10506200). Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure

The "GBGT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GBGT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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