GDAP2: A Potential Drug Target and Biomarker (G54834)

Target Name: GDAP2

NCBI ID: G54834

GDAP2

Other Name(s): MACROD3 | ganglioside-induced differentiation-associated protein 2 | Ganglioside induced differentiation associated protein 2, transcript variant 1 | Ganglioside-induced differentiation-associated protein 2 (isoform a) | Ganglioside-induced differentiation-associated protein 2 | SCAR27 | Ganglioside-Induced differentiation-associated protein 2 (GDAP2) | GDAP2 variant 1 | GDAP2_HUMAN | ganglioside induced differentiation associated protein 2

GDAP2: A Potential Drug Target and Biomarker

Guanocysteine decarboxylase (GDC) alpha-glucosaminidase II (GDAP2) is a protein that is expressed in various tissues and cells in the human body. It is a member of the GDAP family of enzymes that are involved in the metabolism of guanocysteine, a metabolite that is produced by the amino acid cysteine. GDC2 is primarily localized to the endoplasmic reticulum (ER) and is involved in the degradation of GDAP2, which is a potent oncogene that has been implicated in the development and progression of various diseases, including cancer.

GDC2 is a 21-kDa protein that is composed of 158 amino acids. It has a unique structure that consists of a catalytic active site, a 150-amino acid carboxylic acid residue, and a C-terminal glycine residue. GDC2 is a N- glycosylated protein, which means that it has a positively charged N-terminus that is covalently bound to a glycine residue. This positive charge helps to facilitate the interaction between GDC2 and its ligands, which are peptides or small molecules that contain negatively charged amino acids.

GDC2 is involved in the metabolism of guanocysteine, which is a metabolite that is produced by the amino acid cysteine. Cysteine is one of the most common amino acids in the human body and is involved in the production of various proteins, as well as the regulation of various cellular processes. GDC2 is responsible for the efficient degradation of GDAP2, which is a potent oncogene that has been implicated in the development and progression of various diseases, including cancer.

The degradation of GDAP2 by GDC2 is a critical process that helps to maintain the stability and integrity of the endoplasmic reticulum (ER). The ER is a specialized organ that is responsible for the folding and storage of proteins, and it is critical for the regulation of various cellular processes, including cell signaling, DNA replication, and protein synthesis. The degradation of GDAP2 by GDC2 is necessary to remove this oncogene from the ER and prevent it from interacting with other proteins and causing harm.

GDC2 is also involved in the regulation of various cellular processes, including cell signaling, DNA replication, and protein synthesis. GDC2 has been shown to play a role in the regulation of cell signaling pathways, such as the insulin/IGF-1 signaling pathway, which is involved in the regulation of glucose metabolism and energy homeostasis. GDC2 has also been shown to play a role in the regulation of DNA replication, as it has been shown to be involved in the repair of DNA damage. Additionally, GDC2 has been shown to play a role in the regulation of protein synthesis, as it has been shown to be involved in the degradation of proteins that are involved in cell signaling and other cellular processes.

GDC2 is also involved in the regulation of cellular apoptosis, which is a process that helps to remove damaged or dysfunctional cells from the body. GDC2 has been shown to play a role in the regulation of apoptosis in various cellular contexts, including the regulation of neurodegenerative diseases and cancer.

GDC2 is also involved in the regulation of inflammation, as it has been shown to play a role in the regulation of inflammation-related processes. GDC2 has been shown to play a role in the regulation of the production of pro-inflammatory cytokines, as well as the regulation of the production of anti-inflammatory cytokines.

GDC2 is also involved in the regulation of the immune response, as it has been shown to play

Protein Name: Ganglioside Induced Differentiation Associated Protein 2

The "GDAP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GDAP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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