Target Name: TLR3
NCBI ID: G7098
Review Report on TLR3 Target / Biomarker Content of Review Report on TLR3 Target / Biomarker
TLR3
Other Name(s): toll like receptor 3 | Toll like receptor 3 | Toll-like receptor 3 | CD283 | Toll-like receptor 3 (TLR3) | IMD83 | IIAE2 | TLR3_HUMAN

TLR3: Key Target for Drug Development

Toll-like receptor 3 (TLR3) is a protein that is expressed in many different tissues throughout the body. It is a type of immune receptor that is involved in the innate immune system, which is the body's first line of defense against infection. TLR3 is a key mediator of inflammation and is involved in the regulation of various cellular processes that are important for tissue growth and development.

One of the things that makes TLR3 an attractive drug target is its role in the regulation of inflammation. When the body is exposed to an infection, TLR3 helps to trigger an immune response by signaling the activation of various immune cells. This process is important for protecting the body against infection and is a key aspect of the immune system.

Another way that TLR3 is involved in the regulation of inflammation is by its role in the production of pro-inflammatory cytokines. These cytokines, which include factors such as TNF-alpha, IL-1, and IL-6, play a key role in the recruitment of immune cells to the site of inflammation and help to contribute to the inflammatory response. TLR3 is thought to be involved in the production of these cytokines, which may make it an attractive target for drugs that are designed to inhibit inflammation.

In addition to its role in the regulation of inflammation, TLR3 is also involved in the regulation of various cellular processes that are important for tissue growth and development. For example, TLR3 is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. TLR3 also plays a key role in the regulation of cell proliferation, which is the process by which cells grow and divide.

Despite its involvement in a number of important cellular processes, TLR3 is not yet widely understood. While there is some research being done to investigate the role of TLR3 in various biological processes, more research is needed to fully understand its function and to identify potential drug targets.

In conclusion, TLR3 is a protein that is involved in the innate immune system and is thought to play a key role in the regulation of various cellular processes that are important for tissue growth and development. As a result, it is an attractive target for drugs that are designed to modulate inflammation or that promote tissue growth and development. Further research is needed to fully understand the function of TLR3 and to identify potential drug targets.

Protein Name: Toll Like Receptor 3

Functions: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response

The "TLR3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TLR3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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