Target Name: ARHGAP36
NCBI ID: G158763
Review Report on ARHGAP36 Target / Biomarker Content of Review Report on ARHGAP36 Target / Biomarker
ARHGAP36
Other Name(s): Putative Rho GTPase-activating protein FLJ46335 | Rho GTPase activating protein 36 | Rho GTPase-activating protein 36 | RP13-102H20.1 | ARHGAP36 variant 1 | FLJ30058 | Rho GTPase-activating protein 36 (isoform 1) | Rho GTPase activating protein 36, transcript variant 1 | RHG36_HUMAN

ARHGAP36: A Potential Drug Target and Biomarker

ARHGAP36 is a protein that belongs to the ARG/GAP family, which is known for its role in regulating protein-protein interactions and cell signaling pathways. The ARHGAP36 gene has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Disease-Related Functions of ARHGAP36

ARHGAP36 is involved in various cellular processes that are essential for human health, including cell signaling, protein-protein interactions, and DNA replication. It plays a critical role in regulating the activity of the Rho GTPase, which is a protein that plays a central role in cell signaling pathways. The Rho GTPase is a protein that is involved in the regulation of cell proliferation, differentiation, and survival, and it is a potential drug target for several diseases.

ARHGAP36 is also involved in the regulation of the AP-1 gene, which is a transcription factor that is involved in the regulation of various cellular processes, including cell growth, differentiation, and survival. The AP-1 gene has been implicated in the development of several diseases, including cancer, and it is a potential drug target for cancer.

Potential Therapeutic Applications

The potential therapeutic applications for ARHGAP36 are vast and varied. As a drug target, ARHGAP36 can be targeted with small molecules, antibodies, or other therapeutic agents that can modulate its activity and reduce its function in disease. For example, small molecules such as inhibitors of the Rho GTPase can be used to inhibit the activity of ARHGAP36 and reduce its ability to regulate the Rho GTPase. Antibodies that recognize and interact with ARHGAP36 can also be used as therapeutic agents to reduce its activity in disease.

In addition to its potential as a drug target, ARHGAP36 can also be used as a biomarker for several diseases. The ARHGAP36 gene has been shown to be aberrantly expressed in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, ARHGAP36 can be used as a biomarker for these diseases and as a target for diagnostic tests.

Conclusion

In conclusion, ARHGAP36 is a protein that is involved in various cellular processes that are essential for human health. Its role in regulating the Rho GTPase and the AP-1 gene makes it a potential drug target and biomarker for several diseases. The potential therapeutic applications for ARHGAP36 are vast and varied, and its use as a drug target and biomarker is an exciting area of research. Further studies are needed to fully understand the role of ARHGAP36 in disease and to develop effective therapies that can target its activity.

Protein Name: Rho GTPase Activating Protein 36

Functions: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state

The "ARHGAP36 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARHGAP36 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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