ARL4D: A Potential Drug Target and Biomarker (G379)

Target Name: ARL4D

NCBI ID: G379

ARL4D

ARL4D: A Potential Drug Target and Biomarker

Introduction

ARL4D (ADP ribosylation factor like GTPase 4D) is a protein that plays a crucial role in various cellular processes, including cell signaling, DNA replication, and protein synthesis. It is a key player in the RNA polymerase II (RNA-II) complex, which is responsible for synthesizing RNA from DNA templates in the nucleus. ARL4D functions as a GTPase, which means it canGDP-bound and GDP-detached, and it uses this function to regulate the activity of RNA polymerase II.

The discovery of ARL4D as a potential drug target and biomarker has significant implications for the development of new treatments for various diseases. Although ARL4D is involved in many cellular processes, its precise mechanism of action and the specific targets it interacts with have not yet been fully understood. However, research has shown that ARL4D plays a critical role in the regulation of cell proliferation, apoptosis, and inflammation.

ARL4D as a Drug Target

ARL4D has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for cancer growth and progression. One of the main reasons for its potential as a drug target is its role in the regulation of cell proliferation. ARL4D has has been shown to promote the growth and survival of various cancer cell types, including breast, ovarian, and colorectal cancer.

In addition to its role in cell proliferation, ARL4D has also been associated with the regulation of apoptosis, which is the process by which cells die when they have reached their maximum number of copies and are no longer needed. Research shows that ARL4D plays a critical role in the regulation of apoptosis by promoting the survival of vulnerable cells and inhibiting the survival of resistant cells.

ARL4D has also been shown to be involved in the regulation of inflammation, which is a critical part of the immune response. Inflammation is a natural response of the immune system to tissue damage and infection, but chronic inflammation can lead to a range of diseases, including heart disease, diabetes, and cancer.

ARL4D as a Biomarker

The identification of ARL4D as a potential drug target and biomarker has significant implications for the development of new diagnostic tests and therapies. One of the main advantages of ARL4D as a biomarker is its ability to be targeted by small molecules, which makes it an attractive target for drug development. In addition, its involvement in various cellular processes makes it a valuable tool for the study of cellular mechanisms and the development of new therapeutic approaches.

ARL4D has been shown to play a critical role in the regulation of cell signaling, which is a crucial aspect of cellular processes that enable cells to communicate with one another and perform their functions. The regulation of cell signaling is critical for the development and maintenance of various physiological processes, including growth, development, and reproduction.

In conclusion, ARL4D is a protein that plays a critical role in various cellular processes, including cell signaling, DNA replication, and protein synthesis. Its function as a GTPase allows it to regulate the activity of RNA polymerase II, which is responsible for synthesizing RNA from DNA templates in the nucleus. The discovery of ARL4D as a potential drug target and biomarker has significant implications for the development of new treatments for various diseases. Further research is needed to fully understand its mechanism of action and the specific targets it interacts with.

Protein Name: ADP Ribosylation Factor Like GTPase 4D

Functions: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form

The "ARL4D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARL4D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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