ARL8A: A Potential Drug Target and Biomarker (G127829)

Target Name: ARL8A

NCBI ID: G127829

ARL8A

ARL8A: A Potential Drug Target and Biomarker

Introduction

ARL8A (ADP ribosylation factor like GTPase 8A, transcript variant 1) is a gene that encodes a protein involved in various cellular processes, including cell signaling, DNA replication, and protein synthesis. The protein encoded by ARL8A has been shown to play a critical role in regulating mitochondrial function and to be involved in a variety of cellular processes that are related to aging and diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases. As a result, ARL8A has emerged as a promising drug target and biomarker for a variety of diseases.

The Role of ARL8A in Cellular Signaling

ARL8A is a key regulator of mitochondrial function, and its protein has been shown to play a critical role in a variety of cellular signaling pathways. In one such pathway, ARL8A is involved in the regulation of mitochondrial protein synthesis, which is critical for the production of a variety of cellular signaling proteins. In addition, ARL8A is involved in the regulation of mitochondrial dynamics, including the movement of proteins into and out of the mitochondria.

The Role of ARL8A in DNA Replication

ARL8A is also involved in the regulation of DNA replication, a critical process for the development and maintenance of cellular genomes. In DNA replication, ARL8A is shown to play a critical role in the proper assembly and transcription of DNA templates. In addition, ARL8A is involved in the regulation of DNA repair processes, which are critical for the maintenance of cellular genomes.

The Role of ARL8A in Protein Synthesis

In addition to its role in regulating mitochondrial function, ARL8A is also involved in the regulation of protein synthesis. In protein synthesis, ARL8A is shown to play a critical role in the regulation of protein stability and in the pathway responsible for the production of proteins from RNA.

The Role of ARL8A in Aging and Diseases

The regulation of ARL8A by drugs has the potential to treat a variety of diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases. For example, studies have shown that ARL8A is involved in the development and progression of Alzheimer's disease, a neurodegenerative disease that is Characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain. In addition, ARL8A is also involved in the regulation of the mitochondrial dynamics that are altered in many neurodegenerative diseases, including the progression of Parkinson's disease.

In addition to its role in neurodegenerative diseases, ARL8A is also involved in the regulation of cancer cell growth and the development of many types of cancer. For example, studies have shown that ARL8A is involved in the regulation of the growth and survival of cancer cells. , and that inhibition of ARL8A has the potential to be a useful therapeutic approach for cancer treatment.

The Role of ARL8A as a Biomarker

The regulation of ARL8A by drugs has the potential to be a valuable biomarker for a variety of diseases. For example, changes in the level of ARL8A have been shown to be involved in the development and progression of many types of diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases. In addition, the regulation of ARL8A by drugs may also be an effective target for personalized medicine, where treatments are tailored to the specific genetic and molecular profiles of individual patients.

Conclusion

In conclusion, ARL8A is a gene that encodes a protein involved in various cellular processes that are critical for the development and maintenance of cellular genomes. The regulation of ARL8A by drugs has the potential to treat a variety of diseases, including neurodegenerative diseases, cancer, and cardiovascular diseases. As a potential biomarker

Protein Name: ADP Ribosylation Factor Like GTPase 8A

Functions: Plays a role in lysosome motility (By similarity). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity)

The "ARL8A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARL8A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets