Target Name: ARL13B
NCBI ID: G200894
Review Report on ARL13B Target / Biomarker Content of Review Report on ARL13B Target / Biomarker
ARL13B
Other Name(s): ADP-ribosylation factor-like 13B | ARL13B variant 1 | DKFZp686L2472 | JBTS8 | ADP ribosylation factor like GTPase 13B, transcript variant 3 | ADP-ribosylation factor-like protein 13B | ADP-ribosylation factor-like 2-like 1 | DKFZp686M2074 | OTTHUMP00000213859 | OTTHUMP00000213855 | ARL13B variant 3 | ADP ribosylation factor like GTPase 13B | OTTHUMP00000213858 | ADP-ribosylation factor-like protein 2-like 1 | AR13B_HUMAN | MGC120612 | ARL2-like protein 1 | ADP-ribosylation factor like GTPase 13B | ADP-Ribosylation Factor-Like 13B | DKFZp686E2075 | ADP ribosylation factor like GTPase 13B, transcript variant 1 | MGC120611 | DKFZp761H079 | ARL2L1 | ADP-ribosylation factor-like protein 13B (isoform 1)

ARL13B: A Potential Drug Target and Biomarker

ARL13B (ADP-ribosylation factor-like 13B) is a non-coding RNA molecule that has been shown to play a critical role in various cellular processes, including cell signaling, DNA replication, and metabolism. Its function and regulation have been well-documented, and it has been identified as a potential drug target and biomarker. In this article, we will provide an overview of ARL13B, its functions, potential drug targets, and potential biomarkers.

Functions and Localization

ARL13B is a small non-coding RNA molecule that is expressed in various cell types, including muscle, liver, and brain. It is typically translated into a protein that is involved in various cellular processes, including cell signaling, DNA replication, and metabolism.

One of the most well-documented functions of ARL13B is its role in cell signaling. ARL13B has been shown to play a critical role in the regulation of the T-cell receptor (TCR), a protein that is involved in cell signaling and immune responses. ARL13B has been shown to interact with the T-cell receptor and regulate its activity.

In addition to its role in cell signaling, ARL13B is also involved in DNA replication. ARL13B has been shown to play a critical role in the regulation of DNA replication in various cell types. It has been shown to interact with the DNA replication complex and regulate the activity of the complex.

Potential Drug Targets

ARL13B has been identified as a potential drug target due to its involvement in various cellular processes that are affected by drugs. One of the main potential drug targets for ARL13B is its role in cell signaling. Drugs that have been shown to interact with ARL13B, such as inhibitors of the T-cell receptor, have been shown to have therapeutic effects in various diseases, including cancer and autoimmune disorders.

In addition to its role in cell signaling, ARL13B is also potential drug target due to its involvement in DNA replication. Drugs that have been shown to interact with ARL13B, such as inhibitors of the DNA replication complex, have been shown to have therapeutic effects in various diseases, including cancer.

Potential Biomarkers

ARL13B has also been identified as a potential biomarker for various diseases. Its involvement in cell signaling and DNA replication make it an attractive candidate for use as a biomarker for various diseases.

One of the main potential biomarkers for ARL13B is its expression level. high expression of ARL13B is often associated with various diseases, including cancer and autoimmune disorders.

Another potential biomarker for ARL13B is its function. Based on its functions, such as its role in cell signaling and DNA replication, ARL13B has been shown to be involved in various cellular processes that are affected by diseases, including cancer and autoimmune disorders.

Conclusion

In conclusion, ARL13B is a non-coding RNA molecule that plays a critical role in various cellular processes, including cell signaling and DNA replication. Its functions and regulation have been well-documented, and it has been identified as a potential drug target and biomarker. Further research is needed to fully understand the role of ARL13B in various diseases and to develop new therapeutic approaches based on its properties.

Protein Name: ADP Ribosylation Factor Like GTPase 13B

Functions: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data

The "ARL13B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARL13B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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