Target Name: ARHGDIB
NCBI ID: G397
Review Report on ARHGDIB Target / Biomarker Content of Review Report on ARHGDIB Target / Biomarker
ARHGDIB
Other Name(s): RAP1GN1 | GDID4 | Rho GDP dissociation inhibitor beta, transcript variant 1 | rho-GDI beta | RhoGDI2 | Rho GDP dissociation inhibitor beta | D4 | Rho GDI 2 | Ly-GDI | Rho GDP dissociation inhibitor (GDI) beta | Rho-GDI beta | LYGDI | Rho GDP-dissociation inhibitor 2 | ARHGDIB variant 1 | GDIR2_HUMAN | GDIA2

Understanding The Unique Structure and Function of ARHGDIB

ARHGDIB (ARH-GFI-DIB) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a part of the RAP1 gene family, which is known for its role in regulating gene expression and cell signaling.

One of the unique features of ARHGDIB is its structure. It is a transmembrane protein that spans the entire cell membrane, and it contains multiple domains that give it its unique structure and function. The N-terminus of the protein contains a nucleotide-binding oligomerization domain (NBO), which is known for its ability to interact with DNA in a specific way. The C-terminus of the protein contains a leucine-rich repeat (LRR) domain, which is known for its role in protein-protein interactions and may help to regulate the stability of the protein.

The middle of the protein contains a helical region that is known as the transmembrane region (TMR). The TMR is responsible for the protein's ability to span the cell membrane and for its role in cell signaling. It is made up of multiple beta-helices that are arranged in a specific pattern, and it is known for its ability to interact with other proteins and molecules.

ARHGDIB is a protein that is known for its role in several different processes in the body. One of its most well-known functions is its role in the regulation of cell proliferation. It has been shown to play a role in the regulation of cell proliferation in various tissues, including the brain, and it is thought to be involved in the development and progression of cancer.

Another function of ARHGDIB is its role in the regulation of cell death. It has been shown to play a role in the regulation of cell apoptosis (programmed cell death), and it is thought to be involved in the development of neurodegenerative diseases.

ARHGDIB is also known for its role in the regulation of protein synthesis and for its ability to interact with other proteins and molecules. It has been shown to play a role in the regulation of protein synthesis in various tissues, including the brain, and it is thought to be involved in the development and progression of diseases such as diabetes.

In conclusion, ARHGDIB is a protein that is known for its role in several different processes in the body. It is a transmembrane protein that contains multiple domains that give it its unique structure and function. Its unique structure and function have made it an attractive target for research and development, and it is thought to be involved in the regulation of cell proliferation, cell death, and protein synthesis. Further research is needed to fully understand the role of ARHGDIB in the body and its potential as a drug target.

Protein Name: Rho GDP Dissociation Inhibitor Beta

Functions: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133)

The "ARHGDIB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARHGDIB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ARHGDIG | ARHGEF1 | ARHGEF10 | ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 | ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 | ARHGEF2 | ARHGEF25 | ARHGEF26 | ARHGEF26-AS1 | ARHGEF28 | ARHGEF3 | ARHGEF33 | ARHGEF34P | ARHGEF35 | ARHGEF37 | ARHGEF38 | ARHGEF38-IT1 | ARHGEF39 | ARHGEF4 | ARHGEF40 | ARHGEF5 | ARHGEF6 | ARHGEF7 | ARHGEF7-AS1 | ARHGEF9 | ARID1A | ARID1B | ARID2 | ARID3A | ARID3B | ARID3C | ARID4A | ARID4B | ARID5A | ARID5B | ARIH1 | ARIH2 | ARIH2OS | ARIH2P1 | ARL1 | ARL10 | ARL11 | ARL13A | ARL13B | ARL14 | ARL14EP | ARL14EP-DT | ARL14EPL | ARL15 | ARL16 | ARL17A | ARL17B | ARL2 | ARL2-SNX15 | ARL2BP | ARL2BPP2 | ARL3 | ARL4A | ARL4AP2 | ARL4C | ARL4D | ARL5A | ARL5AP4 | ARL5B | ARL5C | ARL6 | ARL6IP1 | ARL6IP1P2 | ARL6IP4 | ARL6IP5 | ARL6IP6 | ARL8A | ARL8B | ARL9 | ARLNC1 | ARMC1 | ARMC10 | ARMC12 | ARMC2 | ARMC3 | ARMC5 | ARMC6 | ARMC7 | ARMC8 | ARMC9 | ARMCX1 | ARMCX2 | ARMCX3 | ARMCX4 | ARMCX5 | ARMCX5-GPRASP2 | ARMCX6 | ARMCX7P | ARMH1