Urolithiasis
About the Disease
Nephrolithiasis, Calcium Oxalate, also known as kidney stones, is related to nephrolithiasis/osteoporosis, hypophosphatemic, 1 and primary hyperoxaluria, and has symptoms including renal pain An important gene associated with Nephrolithiasis, Calcium Oxalate is SLC26A1 (Solute Carrier Family 26 Member 1), and among its related pathways/superpathways are Metabolism and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. The drugs Nifedipine and Potassium citrate have been mentioned in the context of this disorder. Affiliated tissues include Kidney, bone and spinal cord, and related phenotypes are ureteropelvic junction obstruction and acute kidney injury
Common Targets
G846 | G7498 | G5770 | Chymotrypsin (nonspecified subtype) | G116085 | G8654 | G1066 | G155 | G154 | Trypsin (nonspecified subtype) | G3339 | G5444 | Poly [ADP-ribose] polymerase (nonspecified subtype) | G6646 | G10636 | G1636 | G9365 | G1184 | G7124 | G3569 | G84182 | G6696 | G56302 | G7421 | G3553 | G160851 | G148 | Phosphodiesterase 6 (PDE6) (nonspecified subtype) | G999 | G367
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Urolithiasis, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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