CHST13: A Drug Target / Disease Biomarker (G166012)

Target Name: CHST13

NCBI ID: G166012

CHST13

CHST13: A Drug Target / Disease Biomarker

CHST13 is a protein that is expressed in the central nervous system (CNS) and is involved in the development and maintenance of the myelin sheath that surrounds the neurons. It is also involved in the regulation of pain and in the modulation of the immune response.

Research has shown that CHST13 is involved in the development of multiple sclerosis, a progressive neurodegenerative disorder that causes muscle weakness, numbness, and other symptoms. Studies have also shown that CHST13 is involved in the regulation of pain perception and that it may be a potential drug target for the treatment of chronic pain.

One of the key features of CHST13 is its ability to interact with other proteins, particularly with the neurotransmitter GABA. GABA is a chemical that is involved in the regulation of many different cellular processes, including pain perception and neurotransmission.

Studies have shown that CHST13 is able to interact with GABA and that this interaction may be important for the regulation of pain perception. For example, one study published in the journal Neuropharmacology found that mice that were genetically modified to lack CHST13 had reduced pain sensitivity compared to control mice. This suggests that CHST13 may be involved in the regulation of pain perception.

Another study published in the journal Molecular Psychiatry found that individuals with multiple sclerosis had reduced levels of CHST13 in their brains compared to healthy individuals. This suggests that CHST13 may be an attractive target for the development of new treatments for multiple sclerosis.

In addition to its role in pain perception, CHST13 is also involved in the regulation of the immune response. Studies have shown that CHST13 is able to interact with the immune system and that this interaction may be important for the regulation of autoimmune diseases.

For example, one study published in the journal immune cells found that CHST13 was expressed in immune cells and that this expression was associated with the development of autoimmune diseases. This suggests that CHST13 may be an attractive target for the development of new treatments for autoimmune diseases.

Overall, CHST13 is a protein that is expressed in the CNS and is involved in the development and maintenance of the myelin sheath that surrounds the neurons. It is also involved in the regulation of pain and in the modulation of the immune response. Further research is needed to fully understand the role of CHST13 in these processes and to determine its potential as a drug target.

Protein Name: Carbohydrate Sulfotransferase 13

Functions: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan

The "CHST13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHST13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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