ATAD3A: A Potential Drug Target and Biomarker (G55210)

Target Name: ATAD3A

NCBI ID: G55210

ATAD3A

ATAD3A: A Potential Drug Target and Biomarker

ATAD3A, which stands for adenosine triphosphatease A subunit, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the regulation of cellular processes that are involved in the immune response, inflammation, and neurotransmission. In this article, we will discuss ATAD3A and its potential as a drug target or biomarker.

History of ATAD3A

ATAD3A was first identified in the 1970s as a protein that is expressed in the heart, brain, and pancreas. It is composed of three subunits, which are encoded by the genes ATAD3A1, ATAD3A2, and ATAD3A3. The subunits are located on the same chromosome and have similar sequences.

Function of ATAD3A

ATAD3A is involved in the regulation of several cellular processes that are critical for proper cell function. One of its main functions is to regulate the levels of adenosine in the body. Adenosine is a purine nucleoside that plays a crucial role in various cellular processes, including cell signaling, DNA replication, and inflammation.

ATAD3A is involved in the regulation of the levels of adenosine by catalyzing the conversion of adenosine to its active form, adenosine monophosphate (AMP). AMP is a critical signaling molecule that plays a crucial role in cell signaling and communication. It is involved in the regulation of many cellular processes, including cell growth, differentiation, and inflammation.

ATAD3A is also involved in the regulation of the levels of phosphate in the body. Phosphate is a critical macromolecule that plays a crucial role in various cellular processes, including DNA replication, protein synthesis, and signaling.

Drug Targeting

ATAD3A is a potential drug target due to its involvement in the regulation of cellular processes that are involved in the immune response, inflammation, and neurotransmission. Many studies have suggested that blocking the activity of ATAD3A may be a useful way to treat various diseases.

One of the potential mechanisms by which ATAD3A can be targeted is by inhibiting its catalytic activity. This can be done by using small molecules or antibodies that bind to ATAD3A and prevent it from catalyzing the conversion of adenosine to AMP.

Another potential mechanism by which ATAD3A can be targeted is by modifying its structure. This can be done by using drugs that alter ATAD3A's stability or by introducing genetic mutations that alter its function.

Biomarker

ATAD3A is also a potential biomarker for certain diseases. The level of ATAD3A in the body can be measured by using techniques such as Western blotting or immunofluorescence. The level of ATAD3A in the body can also be used as a target for drug testing.

Conclusion

ATAD3A is a protein that is involved in the regulation of various cellular processes that are critical for proper cell function. Its potential as a drug target or biomarker makes it an attractive target for research into the treatment of various diseases. Further studies are needed to fully understand the role of ATAD3A in cellular processes and its potential as a drug target or biomarker.

Protein Name: ATPase Family AAA Domain Containing 3A

Functions: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity (PubMed:31522117)

The "ATAD3A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATAD3A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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