Target Name: ATAD2B
NCBI ID: G54454
Review Report on ATAD2B Target / Biomarker Content of Review Report on ATAD2B Target / Biomarker
ATAD2B
Other Name(s): ATPase family AAA domain containing 2B, transcript variant 1 | ATPase family AAA domain-containing protein 2B | KIAA1240 | ATD2B_HUMAN | ATPase family AAA domain containing 2B | ATPase family AAA domain-containing protein 2B (isoform 1) | ATAD2B variant 1

ATAD2B: A Potential Drug Target and Biomarker

Autosomal Dominant Positive Alignment (ADPA) and Transcriptional Analysis of Development (TAD) are two genes that have been extensively studied in the context of neurodevelopmental diseases. In particular, the study of ATAD2B, a gene that has been implicated in the development and progression of several neurodevelopmental disorders, has gained significant attention in recent years. In this article, we will explore the potential implications of ATAD2B as a drug target and biomarker.

The Importance of ATAD2B

ATAD2B is a gene that has been shown to play a crucial role in the development of several neurodevelopmental disorders, including autism, Down syndrome, and schizophrenia. The symptoms associated with these disorders often include social impairment, communication difficulties, and repetitive behaviors. The exact mechanisms by which these disorders develop are not fully understood, but it is known that they are associated with disruptions in the normal functioning of certain genes, including ATAD2B.

In recent years, researchers have made significant progress in the study of ATAD2B. They have identified several different isoforms of the gene that have been shown to contribute to the development of neurodevelopmental disorders. These isoforms have been shown to have distinct functions in the development of the disorders. For example, one isoform has been shown to play a role in the development of autism, while another isoform has been shown to contribute to the development of Down syndrome.

In addition to its role in the development of neurodevelopmental disorders, ATAD2B has also been shown to be involved in the regulation of normal brain development and function. Studies have shown that the levels of certain proteins that are produced by ATAD2B-expressing cells are altered in the brains of individuals with neurodevelopmental disorders. These proteins have been shown to play important roles in the development and progression of the disorders.

The Potential Implications of ATAD2B as a Drug Target

Given the significant role that ATAD2B plays in the development and progression of neurodevelopmental disorders, it is a promising target for drug development. Researchers have identified several potential drug compounds that have been shown to interact with ATAD2B and have the potential to treat neurodevelopmental disorders.

One of the most promising drug targets associated with ATAD2B is the use of compounds that can modulate the levels of certain proteins that are produced by ATAD2B-expressing cells. These proteins have been shown to play important roles in the development and progression of neurodevelopmental disorders. For example, studies have shown that the levels of the protein synapse-associated protein (SNAP) are altered in the brains of individuals with neurodevelopmental disorders. Compounds that can modulate the levels of SNAP have been shown to have the potential to treat these disorders.

Another potential drug target associated with ATAD2B is the use of compounds that can modulate the levels of certain signaling molecules that are involved in the development and progression of neurodevelopmental disorders. For example, studies have shown that the levels of the neurotransmitter GABA are altered in the brains of individuals with neurodevelopmental disorders. Compounds that can modulate the levels of GABA have been shown to have the potential to treat these disorders.

The Potential Implications of ATAD2B as a Biomarker

In addition to its potential as a drug target, ATAD2B has also been shown to be a potential biomarker for the development and progression of neurodevelopmental disorders. The levels of certain proteins and signaling molecules have been shown to be altered in the brains of individuals with neurodevelopmental disorders, and these changes have been associated with disruptions in the normal functioning of certain genes, including ATAD2B.

Research has shown

Protein Name: ATPase Family AAA Domain Containing 2B

The "ATAD2B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATAD2B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ATAD3A | ATAD3B | ATAD3C | ATAD5 | ATAT1 | ATCAY | ATE1 | ATE1-AS1 | ATF1 | ATF2 | ATF3 | ATF4 | ATF4P2 | ATF4P4 | ATF5 | ATF6 | ATF6-DT | ATF6B | ATF7 | ATF7IP | ATF7IP2 | ATG10 | ATG101 | ATG12 | ATG13 | ATG14 | ATG16L1 | ATG16L2 | ATG2A | ATG2B | ATG3 | ATG4A | ATG4B | ATG4C | ATG4D | ATG5 | ATG7 | ATG9A | ATG9B | ATIC | ATL1 | ATL2 | ATL3 | ATM | ATMIN | ATN1 | ATOH1 | ATOH7 | ATOH8 | ATOSA | ATOSB | ATOX1 | ATOX1-AS1 | ATP Synthase, H+ Transporting, Mitochondrial F0 complex | ATP synthase, H+ transporting, mitochondrial F1 complex | ATP-Binding Cassette (ABC) Transporter | ATP-dependent 6-phosphofructokinase | ATP10A | ATP10B | ATP10D | ATP11A | ATP11A-AS1 | ATP11AUN | ATP11B | ATP11C | ATP12A | ATP13A1 | ATP13A2 | ATP13A3 | ATP13A3-DT | ATP13A4 | ATP13A5 | ATP13A5-AS1 | ATP1A1 | ATP1A1-AS1 | ATP1A2 | ATP1A3 | ATP1A4 | ATP1B1 | ATP1B2 | ATP1B3 | ATP1B4 | ATP23 | ATP2A1 | ATP2A1-AS1 | ATP2A2 | ATP2A3 | ATP2B1 | ATP2B1-AS1 | ATP2B2 | ATP2B3 | ATP2B4 | ATP2C1 | ATP2C2 | ATP4A | ATP4B | ATP5F1A | ATP5F1B | ATP5F1C | ATP5F1D