Target Name: F12
NCBI ID: G2161
Review Report on F12 Target / Biomarker Content of Review Report on F12 Target / Biomarker
F12
Other Name(s): HAF | coagulation factor XIIa light chain | Hageman factor | coagulation factor XII | Beta-factor XIIa part 2 | beta-factor XIIa part 2 | coagulation factor XIIa heavy chain | Beta-factor XIIa part 1 | HAEX | HAE3 | Coagulation factor XII | FA12_HUMAN | beta-factor XIIa part 1 | Coagulation factor XIIa heavy chain | Coagulation factor XIIa light chain

F12 as A Drug Target and Biomarker: Potential Therapies for Cancer and Other Diseases

F12 (fibroblast growth factor-2) is a protein that plays a crucial role in the development and maintenance of tissues, including muscles, skin, and hair. It is a potent regulator of cell growth and differentiation, and has been implicated in a wide range of biological processes. Despite its importance, little is known about F12 as a drug target or biomarker. In this article, we will explore the role of F12 in the context of drug development and its potential as a biomarker for various diseases.

F12 as a Drug Target

F12 has been identified as a potential drug target due to its involvement in several cellular processes that are associated with the development of cancer. For example, F12 has been shown to promote the growth and survival of cancer cells, and has been shown to play a role in the development of neuroendocrine tumors. Additionally, F12 has been shown to contribute to the development of skin and hair tumors.

F12 has also been shown to play a role in the regulation of cell signaling pathways that are involved in the development of autoimmune diseases. For example, F12 has been shown to regulate the production of pro-inflammatory cytokines, which are involved in the development of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

F12 as a Biomarker

F12 has also been shown to be a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, F12 has been shown to be upregulated in the brains of patients with Alzheimer's disease, and has been shown to be involved in the development of neurodegenerative diseases such as Parkinson's disease and Huntington's disease.

F12 has also been shown to be involved in the development of cancer, and has been shown to contribute to the development of several types of cancer, including breast, lung, and ovarian cancer. Additionally, F12 has been shown to be involved in the regulation of cell signaling pathways that are involved in the development of cancer, and has been shown to promote the growth and survival of cancer cells.

Conclusion

In conclusion, F12 is a protein that has been shown to play a role in a wide range of biological processes that are involved in the development and maintenance of tissues. As a drug target, F12 has the potential to contribute to the development of new treatments for a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. As a biomarker, F12 has the potential to be used as a diagnostic tool for the diagnosis of these diseases. Further research is needed to fully understand the role of F12 as a drug target and biomarker, and to explore its potential as a treatment for a wide range of diseases.

Protein Name: Coagulation Factor XII

Functions: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa

The "F12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about F12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1 | F8A2 | F8A3 | F9 | FA2H | FAAH | FAAH2 | FAAHP1 | FAAP100 | FAAP20 | FAAP24 | FABP1 | FABP12 | FABP2 | FABP3 | FABP4 | FABP5 | FABP5P1 | FABP5P10 | FABP5P11 | FABP5P2 | FABP5P3 | FABP5P7 | FABP6 | FABP7 | FABP7P1 | FABP9 | FACT complex | FADD | FADS1 | FADS2 | FADS2B | FADS3 | FADS6 | FAF1 | FAF2 | FAH | FAHD1 | FAHD2A | FAHD2B | FAHD2CP | FAIM | FAIM2 | FALEC | FAM104A | FAM104B | FAM106A | FAM106C | FAM107A | FAM107B | FAM110A | FAM110B | FAM110C | FAM110D | FAM111A | FAM111A-DT | FAM111B | FAM114A1 | FAM114A2 | FAM117A | FAM117B | FAM118A | FAM118B | FAM120A | FAM120A2P | FAM120AOS | FAM120B | FAM120C | FAM124A | FAM124B | FAM131A | FAM131B | FAM131B-AS2 | FAM131C | FAM133A | FAM133B | FAM133CP | FAM133DP | FAM135A | FAM135B | FAM136A | FAM136BP | FAM138A | FAM138B | FAM138C | FAM138D | FAM138F | FAM13A | FAM13A-AS1