Target Name: RASA3
NCBI ID: G22821
Review Report on RASA3 Target / Biomarker Content of Review Report on RASA3 Target / Biomarker
RASA3
Other Name(s): RAS p21 protein activator 3 | RAS p21 protein activator 3, transcript variant 1 | GTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding protein | GAPIII | GAP1IP4BP | ins P4-binding protein | Ins P4-binding protein | MGC46517 | Ras GTPase-activating protein 3 | Ras GTPase-activating protein 3 (isoform 1) | RASA3_HUMAN | GAP1(IP4BP) | Inositol 1,3,4,5-tetrakisphosphate-binding protein | Ins(1,3,4,5)P4-binding protein | MGC47588 | RASA3 variant 1 | GTPase activating protein III

Inhibitors of The RAS P21 Protein

The regulation of gene expression is a critical process in the development and progression of many diseases, including cancer. One of the key factors involved in this regulation is the post-transcriptional modification (RNA modification) of RNA molecules. RNA modifications play a crucial role in the stability, stability, and interactions of RNA molecules, and are involved in the regulation of gene expression.

RAS (Ras-related protein) is a family of transmembrane proteins that are involved in the regulation of gene expression. The RAS gene is located on chromosome 11 and encodes a protein that is essential for cell survival and growth. has four splice variants, which give rise to four distinct isoforms of the RAS protein.

The RAS p21 protein is a key regulator of gene expression in many tissues and is involved in the regulation of cell growth, differentiation, and survival. The RAS p21 protein is a 21-kDa protein that is expressed in many tissues, including the brain, heart, and pancreas. The RAS p21 protein is involved in the regulation of gene expression by binding to specific DNA sequences and modifying the activity of RNA polymerase.

The RAS p21 protein has been implicated in the development and progression of many diseases, including cancer. For example, studies have shown that high levels of RAS p21 are associated with poor prognosis in pancreatic ductal adenocarcinoma (PDAC), a type of cancer that is Characterized by the formation of tumors in the pancreatic duct.

In addition to its role in cancer, the RAS p21 protein is also involved in the regulation of many other physiological processes in the body. For example, the RAS p21 protein is involved in the regulation of cell migration and the maintenance of tissue structure (6 ). The RAS p21 protein is also involved in the regulation of cell survival and has been shown to play a role in the regulation of cell cycle progression.

Given the importance of the RAS p21 protein in many physiological processes, it is a potential drug target or biomarker. The development of compounds that can inhibit the activity of the RAS p21 protein could have a significant impact on the treatment of many diseases.

Targeting the RAS p21 Protein

Several compounds have been shown to inhibit the activity of the RAS p21 protein. These compounds can be classified into two main groups: inhibitors of the RAS p21 protein itself and inhibitors of the RAS-associated protein kinase (RASK).

Inhibitors of the RAS p21 protein itself include compounds that can bind to specific RAS p21 protein subunits and inhibit their activity. For example, studies have shown that inhibitors of the RAS p21 protein can be effective in treating PDAC. In addition, inhibitors of the RAS p21 protein have also been shown to be effective in treating other diseases, including cancer.

Inhibitors of the RAS-associated protein kinase (RASK) have also been shown to be effective in targeting the RAS p21 protein. The RASK is a protein that is involved in the regulation of the activity of the RAS protein, and is thought to play a key role in the regulation of gene expression. Inhibitors of the RASK have been shown to be effective in treating PDAC and other diseases.

Mechanisms of Action

The mechanisms of action of inhibitors of the RAS p21 protein and RASK are not fully understood. However, several studies have shown that these compounds can inhibit the activity of the RAS p21 protein by binding to specific RAS p21 protein subunits and interfering with

Protein Name: RAS P21 Protein Activator 3

Functions: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor

The "RASA3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RASA3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RASA4 | RASA4B | RASA4CP | RASA4DP | RASAL1 | RASAL2 | RASAL2-AS1 | RASAL3 | RASD1 | RASD2 | RASEF | RASGEF1A | RASGEF1B | RASGEF1C | RASGRF1 | RASGRF2 | RASGRP1 | RASGRP2 | RASGRP3 | RASGRP4 | RASIP1 | RASL10A | RASL10B | RASL11A | RASL11B | RASL12 | RASSF1 | RASSF10 | RASSF2 | RASSF3 | RASSF4 | RASSF5 | RASSF6 | RASSF7 | RASSF8 | RASSF8-AS1 | RASSF9 | RAVER1 | RAVER2 | RAX | RAX2 | RB1 | RB1-DT | RB1CC1 | RBAK | RBAK-RBAKDN | RBAKDN | RBBP4 | RBBP4P2 | RBBP4P6 | RBBP5 | RBBP6 | RBBP7 | RBBP8 | RBBP8NL | RBBP9 | RBCK1 | RBFA | RBFOX1 | RBFOX2 | RBFOX3 | RBIS | RBKS | RBL1 | RBL2 | RBM10 | RBM11 | RBM12 | RBM12B | RBM14 | RBM14-RBM4 | RBM15 | RBM15-AS1 | RBM15B | RBM17 | RBM17P1 | RBM18 | RBM19 | RBM20 | RBM22 | RBM22P1 | RBM23 | RBM24 | RBM25 | RBM26 | RBM26-AS1 | RBM27 | RBM28 | RBM3 | RBM33 | RBM34 | RBM38 | RBM39 | RBM4 | RBM41 | RBM42 | RBM43 | RBM43P1 | RBM44 | RBM45